Reply to: “Risks of Organ Preservation in Rectal Cancer: Beyond Distant Metastases, Ultimate Local Failure Can Also Be a Problem,” “Organ Preservation in Rectal Cancer: Fear of Risks Versus the Risks of Fear,” and “Distant Metastases With Nonoperative Management in Rectal Cancer: Challenges in Defining Risk”

Laura M. Fernandez

Laura M. Fernandez, MD, Colorectal Surgery, Digestive Department, Champalimaud Foundation, Lisbon, Portugal; Guilherme P. São Julião, MD, Hospital Alemão Oswaldo Cruz, São Paulo, Brazil, Department of Surgical Oncology, Hospital Beneficencia Portuguesa, São Paulo, Brazil; Carlos Cerdan-Santacruz, MD, Department of Surgery, Hospital de la Princesa, Madrid, Spain; Andrew G. Renehan, MD, Manchester Cancer Research Centre, National Institute of Health and Research Manchester Biomedical Research Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine, and Health, University of Manchester, Manchester, United Kingdom, Colorectal and Peritoneal Oncology Centre, The Christie National Health Service Foundation Trust, Manchester, United Kingdom; Geerard L. Beets, MD, Department of Surgery, Netherlands Cancer Institute, Amsterdam, the Netherlands, GROW School for Oncology and Developmental Biology, Maastricht University, the Netherlands; Amjad Parvaiz, MD and Jose Azevedo, MD, Col...

Guilherme P. São Julião

Laura M. Fernandez, MD, Colorectal Surgery, Digestive Department, Champalimaud Foundation, Lisbon, Portugal; Guilherme P. São Julião, MD, Hospital Alemão Oswaldo Cruz, São Paulo, Brazil, Department of Surgical Oncology, Hospital Beneficencia Portuguesa, São Paulo, Brazil; Carlos Cerdan-Santacruz, MD, Department of Surgery, Hospital de la Princesa, Madrid, Spain; Andrew G. Renehan, MD, Manchester Cancer Research Centre, National Institute of Health and Research Manchester Biomedical Research Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine, and Health, University of Manchester, Manchester, United Kingdom, Colorectal and Peritoneal Oncology Centre, The Christie National Health Service Foundation Trust, Manchester, United Kingdom; Geerard L. Beets, MD, Department of Surgery, Netherlands Cancer Institute, Amsterdam, the Netherlands, GROW School for Oncology and Developmental Biology, Maastricht University, the Netherlands; Amjad Parvaiz, MD and Jose Azevedo, MD, Col...

Carlos Cerdan-Santacruz

Laura M. Fernandez, MD, Colorectal Surgery, Digestive Department, Champalimaud Foundation, Lisbon, Portugal; Guilherme P. São Julião, MD, Hospital Alemão Oswaldo Cruz, São Paulo, Brazil, Department of Surgical Oncology, Hospital Beneficencia Portuguesa, São Paulo, Brazil; Carlos Cerdan-Santacruz, MD, Department of Surgery, Hospital de la Princesa, Madrid, Spain; Andrew G. Renehan, MD, Manchester Cancer Research Centre, National Institute of Health and Research Manchester Biomedical Research Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine, and Health, University of Manchester, Manchester, United Kingdom, Colorectal and Peritoneal Oncology Centre, The Christie National Health Service Foundation Trust, Manchester, United Kingdom; Geerard L. Beets, MD, Department of Surgery, Netherlands Cancer Institute, Amsterdam, the Netherlands, GROW School for Oncology and Developmental Biology, Maastricht University, the Netherlands; Amjad Parvaiz, MD and Jose Azevedo, MD, Col...

Andrew G. Renehan

Laura M. Fernandez, MD, Colorectal Surgery, Digestive Department, Champalimaud Foundation, Lisbon, Portugal; Guilherme P. São Julião, MD, Hospital Alemão Oswaldo Cruz, São Paulo, Brazil, Department of Surgical Oncology, Hospital Beneficencia Portuguesa, São Paulo, Brazil; Carlos Cerdan-Santacruz, MD, Department of Surgery, Hospital de la Princesa, Madrid, Spain; Andrew G. Renehan, MD, Manchester Cancer Research Centre, National Institute of Health and Research Manchester Biomedical Research Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine, and Health, University of Manchester, Manchester, United Kingdom, Colorectal and Peritoneal Oncology Centre, The Christie National Health Service Foundation Trust, Manchester, United Kingdom; Geerard L. Beets, MD, Department of Surgery, Netherlands Cancer Institute, Amsterdam, the Netherlands, GROW School for Oncology and Developmental Biology, Maastricht University, the Netherlands; Amjad Parvaiz, MD and Jose Azevedo, MD, Col...

Geerard L. Beets

Amjad Parvaiz

Laura M. Fernandez, MD, Colorectal Surgery, Digestive Department, Champalimaud Foundation, Lisbon, Portugal; Guilherme P. São Julião, MD, Hospital Alemão Oswaldo Cruz, São Paulo, Brazil, Department of Surgical Oncology, Hospital Beneficencia Portuguesa, São Paulo, Brazil; Carlos Cerdan-Santacruz, MD, Department of Surgery, Hospital de la Princesa, Madrid, Spain; Andrew G. Renehan, MD, Manchester Cancer Research Centre, National Institute of Health and Research Manchester Biomedical Research Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine, and Health, University of Manchester, Manchester, United Kingdom, Colorectal and Peritoneal Oncology Centre, The Christie National Health Service Foundation Trust, Manchester, United Kingdom; Geerard L. Beets, MD, Department of Surgery, Netherlands Cancer Institute, Amsterdam, the Netherlands, GROW School for Oncology and Developmental Biology, Maastricht University, the Netherlands; Amjad Parvaiz, MD and Jose Azevedo, MD, Col...

Jose Azevedo

Laura M. Fernandez, MD, Colorectal Surgery, Digestive Department, Champalimaud Foundation, Lisbon, Portugal; Guilherme P. São Julião, MD, Hospital Alemão Oswaldo Cruz, São Paulo, Brazil, Department of Surgical Oncology, Hospital Beneficencia Portuguesa, São Paulo, Brazil; Carlos Cerdan-Santacruz, MD, Department of Surgery, Hospital de la Princesa, Madrid, Spain; Andrew G. Renehan, MD, Manchester Cancer Research Centre, National Institute of Health and Research Manchester Biomedical Research Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine, and Health, University of Manchester, Manchester, United Kingdom, Colorectal and Peritoneal Oncology Centre, The Christie National Health Service Foundation Trust, Manchester, United Kingdom; Geerard L. Beets, MD, Department of Surgery, Netherlands Cancer Institute, Amsterdam, the Netherlands, GROW School for Oncology and Developmental Biology, Maastricht University, the Netherlands; Amjad Parvaiz, MD and Jose Azevedo, MD, Col...

Bruna B. Vailati

Laura M. Fernandez, MD, Colorectal Surgery, Digestive Department, Champalimaud Foundation, Lisbon, Portugal; Guilherme P. São Julião, MD, Hospital Alemão Oswaldo Cruz, São Paulo, Brazil, Department of Surgical Oncology, Hospital Beneficencia Portuguesa, São Paulo, Brazil; Carlos Cerdan-Santacruz, MD, Department of Surgery, Hospital de la Princesa, Madrid, Spain; Andrew G. Renehan, MD, Manchester Cancer Research Centre, National Institute of Health and Research Manchester Biomedical Research Centre, Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology, Medicine, and Health, University of Manchester, Manchester, United Kingdom, Colorectal and Peritoneal Oncology Centre, The Christie National Health Service Foundation Trust, Manchester, United Kingdom; Geerard L. Beets, MD, Department of Surgery, Netherlands Cancer Institute, Amsterdam, the Netherlands, GROW School for Oncology and Developmental Biology, Maastricht University, the Netherlands; Amjad Parvaiz, MD and Jose Azevedo, MD, Col...

Rodrigo O. Perez

Department of Surgical Oncology, Hospital Alemão Oswaldo Cruz, São Paulo, Brazil