Reply to: “ <i>NOTCH1</i> : A Potential New Biomarker in the Era of Immunotherapy?” and “Caution in Interpreting <i>NOTCH1</i> Mutation as a Predictive Biomarker of Tislelizumab Response in Esophageal Squamous Cell Carcinoma”

Zhihao Lu

Key Laboratory of Life‐Organic Analysis of Shandong Province School of Chemistry and Chemical Engineering Qufu Normal University Qufu 273165 P.R. China

Wenting Du

Zhihao Lu, MD, Department of Gastrointestinal Oncology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital &amp; Institute, Beijing, China; Wenting Du, PhD, Clinical Biomarker, BeOne Medicines, Ltd, Shanghai, China; Xi Jiao, MD, and Yanni Wang, PhD, Department of Gastrointestinal Oncology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital &amp; Institute, Beijing, China; Zhang Zhang, PhD, Statistics, BeOne Medicines, Ltd, Beijing, China; and Lin Shen, MD, Department of Gastrointestinal Oncology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital &amp; Institute, Beijing, China, State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Beijing Key Laboratory of Carcinogenesis and Translational Research, Department of Gastrointestinal Oncology, Peking University Cancer Hospital &a...

Xi Jiao

Zhihao Lu, MD, Department of Gastrointestinal Oncology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital &amp; Institute, Beijing, China; Wenting Du, PhD, Clinical Biomarker, BeOne Medicines, Ltd, Shanghai, China; Xi Jiao, MD, and Yanni Wang, PhD, Department of Gastrointestinal Oncology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital &amp; Institute, Beijing, China; Zhang Zhang, PhD, Statistics, BeOne Medicines, Ltd, Beijing, China; and Lin Shen, MD, Department of Gastrointestinal Oncology, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital &amp; Institute, Beijing, China, State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers, Beijing Key Laboratory of Carcinogenesis and Translational Research, Department of Gastrointestinal Oncology, Peking University Cancer Hospital &a...

Yanni Wang

Zhang Zhang

State Key Laboratory of Bioactive Molecules and Druggability Assessment, and School of Pharmacy, Jinan University, 601 Huangpu Avenue West, Guangzhou 510632, China

Lin Shen