Reply to: “Beyond Response Rates: Interpreting Long-Term Benefit in CheckMate 743” and “Beyond Statistical Significance: Methodological Fragility and Censoring Bias in the 5-Year Update of CheckMate 743”

Arnaud Scherpereel

Arnaud Scherpereel, MD, PhD, CHU Lille, Univ. Lille, Inserm, U1366-UMR9020—CRCLille—Cancer Research Center of Lille, OncoThAI, ONCOLille, Lille, France; Aaron S. Mansfield, MD, Mayo Clinic, Rochester, MN; Francesco Grossi, MD, Medical Oncology Division, Department of Medicine and Technological Innovation, University of Insubria, Varese, Italy; Sanjay Popat, PhD, FRCP, The Royal Marsden Hospital, London, United Kingdom; Paul Baas, MD, PhD, The Netherlands Cancer Institute and Leiden University Medical Center, Amsterdam, the Netherlands; Anna K. Nowak, PhD, MBBS, University of Western Australia, Perth, WA, Australia; Anne S. Tsao, MD, MBA, University of Texas MD Anderson Cancer Center, Houston, TX; Nobukazu Fujimoto, MD, PhD, Okayama Rosai Hospital, Okayama, Japan; Solange Peters, MD, PhD, Lausanne University Hospital, Lausanne, Switzerland; Yolanda Bautista Aragon, MD, Centro Médico Nacional Siglo XXI, Mexico City, Mexico; Toby Talbot, MD, The Sunrise Centre, Royal Cornwall Hospitals NHS Trust, Truro, Unite...

Aaron S. Mansfield

Francesco Grossi

Arnaud Scherpereel, MD, PhD, CHU Lille, Univ. Lille, Inserm, U1366-UMR9020—CRCLille—Cancer Research Center of Lille, OncoThAI, ONCOLille, Lille, France; Aaron S. Mansfield, MD, Mayo Clinic, Rochester, MN; Francesco Grossi, MD, Medical Oncology Division, Department of Medicine and Technological Innovation, University of Insubria, Varese, Italy; Sanjay Popat, PhD, FRCP, The Royal Marsden Hospital, London, United Kingdom; Paul Baas, MD, PhD, The Netherlands Cancer Institute and Leiden University Medical Center, Amsterdam, the Netherlands; Anna K. Nowak, PhD, MBBS, University of Western Australia, Perth, WA, Australia; Anne S. Tsao, MD, MBA, University of Texas MD Anderson Cancer Center, Houston, TX; Nobukazu Fujimoto, MD, PhD, Okayama Rosai Hospital, Okayama, Japan; Solange Peters, MD, PhD, Lausanne University Hospital, Lausanne, Switzerland; Yolanda Bautista Aragon, MD, Centro Médico Nacional Siglo XXI, Mexico City, Mexico; Toby Talbot, MD, The Sunrise Centre, Royal Cornwall Hospitals NHS Trust, Truro, Unite...

Sanjay Popat

Paul Baas

Arnaud Scherpereel, MD, PhD, CHU Lille, Univ. Lille, Inserm, U1366-UMR9020—CRCLille—Cancer Research Center of Lille, OncoThAI, ONCOLille, Lille, France; Aaron S. Mansfield, MD, Mayo Clinic, Rochester, MN; Francesco Grossi, MD, Medical Oncology Division, Department of Medicine and Technological Innovation, University of Insubria, Varese, Italy; Sanjay Popat, PhD, FRCP, The Royal Marsden Hospital, London, United Kingdom; Paul Baas, MD, PhD, The Netherlands Cancer Institute and Leiden University Medical Center, Amsterdam, the Netherlands; Anna K. Nowak, PhD, MBBS, University of Western Australia, Perth, WA, Australia; Anne S. Tsao, MD, MBA, University of Texas MD Anderson Cancer Center, Houston, TX; Nobukazu Fujimoto, MD, PhD, Okayama Rosai Hospital, Okayama, Japan; Solange Peters, MD, PhD, Lausanne University Hospital, Lausanne, Switzerland; Yolanda Bautista Aragon, MD, Centro Médico Nacional Siglo XXI, Mexico City, Mexico; Toby Talbot, MD, The Sunrise Centre, Royal Cornwall Hospitals NHS Trust, Truro, Unite...

Anna K. Nowak

Arnaud Scherpereel, MD, PhD, CHU Lille, Univ. Lille, Inserm, U1366-UMR9020—CRCLille—Cancer Research Center of Lille, OncoThAI, ONCOLille, Lille, France; Aaron S. Mansfield, MD, Mayo Clinic, Rochester, MN; Francesco Grossi, MD, Medical Oncology Division, Department of Medicine and Technological Innovation, University of Insubria, Varese, Italy; Sanjay Popat, PhD, FRCP, The Royal Marsden Hospital, London, United Kingdom; Paul Baas, MD, PhD, The Netherlands Cancer Institute and Leiden University Medical Center, Amsterdam, the Netherlands; Anna K. Nowak, PhD, MBBS, University of Western Australia, Perth, WA, Australia; Anne S. Tsao, MD, MBA, University of Texas MD Anderson Cancer Center, Houston, TX; Nobukazu Fujimoto, MD, PhD, Okayama Rosai Hospital, Okayama, Japan; Solange Peters, MD, PhD, Lausanne University Hospital, Lausanne, Switzerland; Yolanda Bautista Aragon, MD, Centro Médico Nacional Siglo XXI, Mexico City, Mexico; Toby Talbot, MD, The Sunrise Centre, Royal Cornwall Hospitals NHS Trust, Truro, Unite...

Anne S. Tsao

Arnaud Scherpereel, MD, PhD, CHU Lille, Univ. Lille, Inserm, U1366-UMR9020—CRCLille—Cancer Research Center of Lille, OncoThAI, ONCOLille, Lille, France; Aaron S. Mansfield, MD, Mayo Clinic, Rochester, MN; Francesco Grossi, MD, Medical Oncology Division, Department of Medicine and Technological Innovation, University of Insubria, Varese, Italy; Sanjay Popat, PhD, FRCP, The Royal Marsden Hospital, London, United Kingdom; Paul Baas, MD, PhD, The Netherlands Cancer Institute and Leiden University Medical Center, Amsterdam, the Netherlands; Anna K. Nowak, PhD, MBBS, University of Western Australia, Perth, WA, Australia; Anne S. Tsao, MD, MBA, University of Texas MD Anderson Cancer Center, Houston, TX; Nobukazu Fujimoto, MD, PhD, Okayama Rosai Hospital, Okayama, Japan; Solange Peters, MD, PhD, Lausanne University Hospital, Lausanne, Switzerland; Yolanda Bautista Aragon, MD, Centro Médico Nacional Siglo XXI, Mexico City, Mexico; Toby Talbot, MD, The Sunrise Centre, Royal Cornwall Hospitals NHS Trust, Truro, Unite...

Nobukazu Fujimoto

Solange Peters

Yolanda Bautista Aragon

Arnaud Scherpereel, MD, PhD, CHU Lille, Univ. Lille, Inserm, U1366-UMR9020—CRCLille—Cancer Research Center of Lille, OncoThAI, ONCOLille, Lille, France; Aaron S. Mansfield, MD, Mayo Clinic, Rochester, MN; Francesco Grossi, MD, Medical Oncology Division, Department of Medicine and Technological Innovation, University of Insubria, Varese, Italy; Sanjay Popat, PhD, FRCP, The Royal Marsden Hospital, London, United Kingdom; Paul Baas, MD, PhD, The Netherlands Cancer Institute and Leiden University Medical Center, Amsterdam, the Netherlands; Anna K. Nowak, PhD, MBBS, University of Western Australia, Perth, WA, Australia; Anne S. Tsao, MD, MBA, University of Texas MD Anderson Cancer Center, Houston, TX; Nobukazu Fujimoto, MD, PhD, Okayama Rosai Hospital, Okayama, Japan; Solange Peters, MD, PhD, Lausanne University Hospital, Lausanne, Switzerland; Yolanda Bautista Aragon, MD, Centro Médico Nacional Siglo XXI, Mexico City, Mexico; Toby Talbot, MD, The Sunrise Centre, Royal Cornwall Hospitals NHS Trust, Truro, Unite...

Toby Talbot

Arnaud Scherpereel, MD, PhD, CHU Lille, Univ. Lille, Inserm, U1366-UMR9020—CRCLille—Cancer Research Center of Lille, OncoThAI, ONCOLille, Lille, France; Aaron S. Mansfield, MD, Mayo Clinic, Rochester, MN; Francesco Grossi, MD, Medical Oncology Division, Department of Medicine and Technological Innovation, University of Insubria, Varese, Italy; Sanjay Popat, PhD, FRCP, The Royal Marsden Hospital, London, United Kingdom; Paul Baas, MD, PhD, The Netherlands Cancer Institute and Leiden University Medical Center, Amsterdam, the Netherlands; Anna K. Nowak, PhD, MBBS, University of Western Australia, Perth, WA, Australia; Anne S. Tsao, MD, MBA, University of Texas MD Anderson Cancer Center, Houston, TX; Nobukazu Fujimoto, MD, PhD, Okayama Rosai Hospital, Okayama, Japan; Solange Peters, MD, PhD, Lausanne University Hospital, Lausanne, Switzerland; Yolanda Bautista Aragon, MD, Centro Médico Nacional Siglo XXI, Mexico City, Mexico; Toby Talbot, MD, The Sunrise Centre, Royal Cornwall Hospitals NHS Trust, Truro, Unite...

Dariusz Kowalski

Narodowy Instytut Onkologii im. Marii Skłodowskiej-Curie Państwowy Instytut Badawczy, Klinika Nowotworow Pluca i Klatki Piersiowej, Warsaw, Poland

Muhammet A. Kaplan

Arnaud Scherpereel, MD, PhD, CHU Lille, Univ. Lille, Inserm, U1366-UMR9020—CRCLille—Cancer Research Center of Lille, OncoThAI, ONCOLille, Lille, France; Aaron S. Mansfield, MD, Mayo Clinic, Rochester, MN; Francesco Grossi, MD, Medical Oncology Division, Department of Medicine and Technological Innovation, University of Insubria, Varese, Italy; Sanjay Popat, PhD, FRCP, The Royal Marsden Hospital, London, United Kingdom; Paul Baas, MD, PhD, The Netherlands Cancer Institute and Leiden University Medical Center, Amsterdam, the Netherlands; Anna K. Nowak, PhD, MBBS, University of Western Australia, Perth, WA, Australia; Anne S. Tsao, MD, MBA, University of Texas MD Anderson Cancer Center, Houston, TX; Nobukazu Fujimoto, MD, PhD, Okayama Rosai Hospital, Okayama, Japan; Solange Peters, MD, PhD, Lausanne University Hospital, Lausanne, Switzerland; Yolanda Bautista Aragon, MD, Centro Médico Nacional Siglo XXI, Mexico City, Mexico; Toby Talbot, MD, The Sunrise Centre, Royal Cornwall Hospitals NHS Trust, Truro, Unite...

Andrés Felipe Cardona

Arnaud Scherpereel, MD, PhD, CHU Lille, Univ. Lille, Inserm, U1366-UMR9020—CRCLille—Cancer Research Center of Lille, OncoThAI, ONCOLille, Lille, France; Aaron S. Mansfield, MD, Mayo Clinic, Rochester, MN; Francesco Grossi, MD, Medical Oncology Division, Department of Medicine and Technological Innovation, University of Insubria, Varese, Italy; Sanjay Popat, PhD, FRCP, The Royal Marsden Hospital, London, United Kingdom; Paul Baas, MD, PhD, The Netherlands Cancer Institute and Leiden University Medical Center, Amsterdam, the Netherlands; Anna K. Nowak, PhD, MBBS, University of Western Australia, Perth, WA, Australia; Anne S. Tsao, MD, MBA, University of Texas MD Anderson Cancer Center, Houston, TX; Nobukazu Fujimoto, MD, PhD, Okayama Rosai Hospital, Okayama, Japan; Solange Peters, MD, PhD, Lausanne University Hospital, Lausanne, Switzerland; Yolanda Bautista Aragon, MD, Centro Médico Nacional Siglo XXI, Mexico City, Mexico; Toby Talbot, MD, The Sunrise Centre, Royal Cornwall Hospitals NHS Trust, Truro, Unite...

Raheela Soomro

3Cogent Biosciences Inc., Waltham, United States

Nan Hu

Adam Lee

Division of Cardiology (G.M.M., E.P.G., H.H., A.L., J.M., G.W., K.C., M.Y., G.M.), University of California, San Francisco.

Virginia Ip

Arnaud Scherpereel, MD, PhD, CHU Lille, Univ. Lille, Inserm, U1366-UMR9020—CRCLille—Cancer Research Center of Lille, OncoThAI, ONCOLille, Lille, France; Aaron S. Mansfield, MD, Mayo Clinic, Rochester, MN; Francesco Grossi, MD, Medical Oncology Division, Department of Medicine and Technological Innovation, University of Insubria, Varese, Italy; Sanjay Popat, PhD, FRCP, The Royal Marsden Hospital, London, United Kingdom; Paul Baas, MD, PhD, The Netherlands Cancer Institute and Leiden University Medical Center, Amsterdam, the Netherlands; Anna K. Nowak, PhD, MBBS, University of Western Australia, Perth, WA, Australia; Anne S. Tsao, MD, MBA, University of Texas MD Anderson Cancer Center, Houston, TX; Nobukazu Fujimoto, MD, PhD, Okayama Rosai Hospital, Okayama, Japan; Solange Peters, MD, PhD, Lausanne University Hospital, Lausanne, Switzerland; Yolanda Bautista Aragon, MD, Centro Médico Nacional Siglo XXI, Mexico City, Mexico; Toby Talbot, MD, The Sunrise Centre, Royal Cornwall Hospitals NHS Trust, Truro, Unite...

Yu-Han Hung

Arnaud Scherpereel, MD, PhD, CHU Lille, Univ. Lille, Inserm, U1366-UMR9020—CRCLille—Cancer Research Center of Lille, OncoThAI, ONCOLille, Lille, France; Aaron S. Mansfield, MD, Mayo Clinic, Rochester, MN; Francesco Grossi, MD, Medical Oncology Division, Department of Medicine and Technological Innovation, University of Insubria, Varese, Italy; Sanjay Popat, PhD, FRCP, The Royal Marsden Hospital, London, United Kingdom; Paul Baas, MD, PhD, The Netherlands Cancer Institute and Leiden University Medical Center, Amsterdam, the Netherlands; Anna K. Nowak, PhD, MBBS, University of Western Australia, Perth, WA, Australia; Anne S. Tsao, MD, MBA, University of Texas MD Anderson Cancer Center, Houston, TX; Nobukazu Fujimoto, MD, PhD, Okayama Rosai Hospital, Okayama, Japan; Solange Peters, MD, PhD, Lausanne University Hospital, Lausanne, Switzerland; Yolanda Bautista Aragon, MD, Centro Médico Nacional Siglo XXI, Mexico City, Mexico; Toby Talbot, MD, The Sunrise Centre, Royal Cornwall Hospitals NHS Trust, Truro, Unite...

Gérard Zalcman

Arnaud Scherpereel, MD, PhD, CHU Lille, Univ. Lille, Inserm, U1366-UMR9020—CRCLille—Cancer Research Center of Lille, OncoThAI, ONCOLille, Lille, France; Aaron S. Mansfield, MD, Mayo Clinic, Rochester, MN; Francesco Grossi, MD, Medical Oncology Division, Department of Medicine and Technological Innovation, University of Insubria, Varese, Italy; Sanjay Popat, PhD, FRCP, The Royal Marsden Hospital, London, United Kingdom; Paul Baas, MD, PhD, The Netherlands Cancer Institute and Leiden University Medical Center, Amsterdam, the Netherlands; Anna K. Nowak, PhD, MBBS, University of Western Australia, Perth, WA, Australia; Anne S. Tsao, MD, MBA, University of Texas MD Anderson Cancer Center, Houston, TX; Nobukazu Fujimoto, MD, PhD, Okayama Rosai Hospital, Okayama, Japan; Solange Peters, MD, PhD, Lausanne University Hospital, Lausanne, Switzerland; Yolanda Bautista Aragon, MD, Centro Médico Nacional Siglo XXI, Mexico City, Mexico; Toby Talbot, MD, The Sunrise Centre, Royal Cornwall Hospitals NHS Trust, Truro, Unite...