Remodeling of the immune microenvironment is linked to adverse outcome in pediatric T cell acute lymphoblastic leukemia

Caroline R. M. Wiggers; Eugene Y. Cho; Merve Ozdemir; Gbolahan Bamgbose; Justin Hegel; Julia Frede; Frederike Warlitz; Tayla B. Heavican-Foral; Ioana Pop; Rawan Shraim; Petri Pölönen; Victoria Koch; Thai Hoa Tran; Charles G. Mullighan; David T. Teachey; Jacob R. Bledsoe; Yana Pikman; Marian H. Harris; Andrew E. Place; Lewis B. Silverman; Jens G. Lohr; Birgit Knoechel

doi:10.1038/s41467-025-65134-y

Remodeling of the immune microenvironment is linked to adverse outcome in pediatric T cell acute lymphoblastic leukemia

C Caroline R. M. Wiggers E Eugene Y. Cho M Merve Ozdemir G Gbolahan Bamgbose J Justin Hegel J Julia Frede F Frederike Warlitz T Tayla B. Heavican-Foral I Ioana Pop R Rawan Shraim P Petri Pölönen V Victoria Koch T Thai Hoa Tran C Charles G. Mullighan D David T. Teachey J Jacob R. Bledsoe Y Yana Pikman M Marian H. Harris A Andrew E. Place L Lewis B. Silverman J Jens G. Lohr B Birgit Knoechel

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Article Details

Journal Nature Communications

Volume / Issue Vol. 16, Issue 1

Published November 21, 2025

DOI 10.1038/s41467-025-65134-y

ISSN 2041-1723

Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (22)

C

Caroline R. M. Wiggers

E

Eugene Y. Cho

M

Merve Ozdemir

G

Gbolahan Bamgbose

J

Justin Hegel

J

Julia Frede

F

Frederike Warlitz

T

Tayla B. Heavican-Foral

I

Ioana Pop

R

Rawan Shraim

P

Petri Pölönen

V

Victoria Koch

T

Thai Hoa Tran

C

Charles G. Mullighan

D

David T. Teachey

J

Jacob R. Bledsoe

Y

Yana Pikman

M

Marian H. Harris

A

Andrew E. Place

L

Lewis B. Silverman

J

Jens G. Lohr

B

Birgit Knoechel

Remodeling of the immune microenvironment is linked to adverse outcome in pediatric T cell acute lymphoblastic leukemia

Article Details

Journal Info

Authors (22)

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