Relationship between sortilin with ApoB/ApoA ratio in military personnel with arterial hypertension

Abstract

Abstract The study investigates the relationship between sortilin levels and the ApoB/ApoA ratio in military personnel with arterial hypertension. A cross-sectional analytical study involving 120 male military personnel was conducted. Biochemical, hematological, and ELISA measurements were performed. Sortilin, ApoB, ApoB/ApoA ratio, and hs-CRP levels were significantly higher in the hypertensive group and correlated with systolic blood pressure. ROC analysis confirmed their discriminatory performance. Sortilin, ApoB, and hs-CRP are associated with hypertension and may be considered potential markers related to cardiovascular risk. However, due to the cross-sectional design, causal relationships cannot be established, and further large-scale prospective studies are required.