Recessive variants in the intergenic NOS1AP-C1orf226 locus cause monogenic kidney disease responsive to anti-proteinuric treatment

Florian Buerger; Daanya Salmanullah; Lorrin Liang; Victoria Gauntner; Kavita Krueger; Jiansong Qi; Josee Normand; Vineeta Sharma; Arathi Ranga; Alexander Rubin; David Ball; Sunwoo Hong; Katharina Lemberg; Ken Saida; Lea Maria Merz; Sanja Sever; Biju Issac; Qianyi Ma; Liang Sun; Anja M. Billing; Fatih Demir; Markus M. Rinschen; Björn Reusch; Bodo B. Beck; Sergio Guerrero-Castillo; Alexis C. Gomez; Michelle T. McNulty; Matthew G. Sampson; Mohamed H. Al-Hamed; Mohammed M. Saleh; Mohamed A. Shalaby; Jameela A. Kari; James P. Fawcett; Friedhelm Hildebrandt; Amar J. Majmundar

doi:10.1038/s41467-025-65663-6

Recessive variants in the intergenic NOS1AP-C1orf226 locus cause monogenic kidney disease responsive to anti-proteinuric treatment

F Florian Buerger D Daanya Salmanullah L Lorrin Liang V Victoria Gauntner K Kavita Krueger J Jiansong Qi J Josee Normand V Vineeta Sharma A Arathi Ranga A Alexander Rubin D David Ball S Sunwoo Hong K Katharina Lemberg K Ken Saida L Lea Maria Merz S Sanja Sever B Biju Issac Q Qianyi Ma (Department of Chemical Engineering, Waterloo Institute for Nanotechnology, University of Waterloo, 200 University Avenue West, Waterloo, Ontario N2L 3G1, Canada) L Liang Sun A Anja M. Billing F Fatih Demir M Markus M. Rinschen B Björn Reusch B Bodo B. Beck S Sergio Guerrero-Castillo A Alexis C. Gomez M Michelle T. McNulty M Matthew G. Sampson M Mohamed H. Al-Hamed M Mohammed M. Saleh M Mohamed A. Shalaby J Jameela A. Kari J James P. Fawcett F Friedhelm Hildebrandt A Amar J. Majmundar

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Article Details

Journal Nature Communications

Volume / Issue Vol. 16, Issue 1

Published November 27, 2025

DOI 10.1038/s41467-025-65663-6

ISSN 2041-1723

Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (35)

F

Florian Buerger

D

Daanya Salmanullah

L

Lorrin Liang

V

Victoria Gauntner

K

Kavita Krueger

J

Jiansong Qi

J

Josee Normand

V

Vineeta Sharma

A

Arathi Ranga

A

Alexander Rubin

D

David Ball

S

Sunwoo Hong

K

Katharina Lemberg

K

Ken Saida

L

Lea Maria Merz

S

Sanja Sever

B

Biju Issac

Q

Qianyi Ma

Department of Chemical Engineering, Waterloo Institute for Nanotechnology, University of Waterloo, 200 University Avenue West, Waterloo, Ontario N2L 3G1, Canada

L

Liang Sun

A

Anja M. Billing

F

Fatih Demir

M

Markus M. Rinschen

B

Björn Reusch

B

Bodo B. Beck

S

Sergio Guerrero-Castillo

A

Alexis C. Gomez

M

Michelle T. McNulty

M

Matthew G. Sampson

M

Mohamed H. Al-Hamed

M

Mohammed M. Saleh

M

Mohamed A. Shalaby

J

Jameela A. Kari

J

James P. Fawcett

F

Friedhelm Hildebrandt

A

Amar J. Majmundar

Recessive variants in the intergenic NOS1AP-C1orf226 locus cause monogenic kidney disease responsive to anti-proteinuric treatment

Article Details

Journal Info

Authors (35)

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