Recapitulating hypoxic metabolism in cartilaginous organoids via adaptive cell-matrix interactions enhances histone lactylation and cartilage regeneration

B Boguang Yang Z Zhuo Li Z Zhengmeng Yang P Pengchao Zhao (School of Biomedical Sciences and Engineering, Guangzhou International Campus) S Sien Lin (Department of Orthopaedics and Traumatology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine) J Jiahao Wu W Wei Liu X Xuefeng Yang (Laboratory of Nanosystem and Hierarchical Fabrication) X Xian Xie (Department of Biomedical Engineering) Z Zhixian Zong Y Yuanning Lyu Z Zhinan Yang G Gang Li (State Key Laboratory of Molecular Reaction Dynamics and Dalian Coherent Light Source Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023, China) T To Ngai K Kunyu Zhang (School of Biomedical Sciences and Engineering, Guangzhou International Campus) L Liming Bian (School of Biomedical Sciences and Engineering, Guangzhou International Campus)

Article Details

Volume / Issue Vol. 16, Issue 1
Published March 19, 2025
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (16)

B

Boguang Yang

Z

Zhuo Li

Z

Zhengmeng Yang

P

Pengchao Zhao

School of Biomedical Sciences and Engineering, Guangzhou International Campus

S

Sien Lin

Department of Orthopaedics and Traumatology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine

J

Jiahao Wu

W

Wei Liu

X

Xuefeng Yang

Laboratory of Nanosystem and Hierarchical Fabrication

X

Xian Xie

Department of Biomedical Engineering

Z

Zhixian Zong

Y

Yuanning Lyu

Z

Zhinan Yang

G

Gang Li

State Key Laboratory of Molecular Reaction Dynamics and Dalian Coherent Light Source Dalian Institute of Chemical Physics, Chinese Academy of Sciences, 457 Zhongshan Road, Dalian 116023, China

T

To Ngai

K

Kunyu Zhang

School of Biomedical Sciences and Engineering, Guangzhou International Campus

L

Liming Bian

School of Biomedical Sciences and Engineering, Guangzhou International Campus