PTBP1 inhibition reprograms myogenesis to rescue impaired muscle regeneration in mdx mice through correcting E2A splicing

S Shusheng Fan X Xiaoyun Liu Q Qian Pan (Frontier Innovation Center, Department of Systems Biology for Medicine, Qidong-Fudan Innovative Institution of Medical Sciences, School of Basic Medical Sciences, Fudan University) H Haowei Tong Q Qiaoqiao Gui G Guangyao Guo H Huitao Hong W Wanting Hu X Xiaofei Huang L Lei Zhao (School of Life Sciences, Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, and Hubei Key Laboratory of Genetic Regulation and Integrative Biology, Central China Normal University) X Xihua Li Q Qinwei Yu L Luyong Zhang (Research Center for Crystal Materials, CAS Key Laboratory of Functional Materials and Devices for Special Environmental Conditions, Xinjiang Key Laboratory of Functional Crystal Materials, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, 40-1 South Beijing Road, Urumqi 830011, China) Z Zhenzhou Jiang

Article Details

Volume / Issue Vol. 17, Issue 1
Published March 12, 2026
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (14)

S

Shusheng Fan

X

Xiaoyun Liu

Q

Qian Pan

Frontier Innovation Center, Department of Systems Biology for Medicine, Qidong-Fudan Innovative Institution of Medical Sciences, School of Basic Medical Sciences, Fudan University

H

Haowei Tong

Q

Qiaoqiao Gui

G

Guangyao Guo

H

Huitao Hong

W

Wanting Hu

X

Xiaofei Huang

L

Lei Zhao

School of Life Sciences, Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, and Hubei Key Laboratory of Genetic Regulation and Integrative Biology, Central China Normal University

X

Xihua Li

Q

Qinwei Yu

L

Luyong Zhang

Research Center for Crystal Materials, CAS Key Laboratory of Functional Materials and Devices for Special Environmental Conditions, Xinjiang Key Laboratory of Functional Crystal Materials, Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, 40-1 South Beijing Road, Urumqi 830011, China

Z

Zhenzhou Jiang