Proximity-Driven Protein Ligation Beyond the Concentration Limit

J Jianhui Yin (Shanghai Key Laboratory for Antibody-Drug Conjugates with Innovative Target, National Key Laboratory of Innovative Immunotherapy, School of Chemistry and Chemical Engineering) X Xinliang Liu (Center for Chemical Glycobiology, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Zhangjiang Institute for Advanced Study, School of Pharmaceutical Sciences) Z Zhe Meng (Shanghai Key Laboratory for Antibody-Drug Conjugates with Innovative Target, National Key Laboratory of Innovative Immunotherapy, School of Chemistry and Chemical Engineering) Y Yixiang Shi (Center for Chemical Glycobiology, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Zhangjiang Institute for Advanced Study, School of Pharmaceutical Sciences) G Guofeng Zhang (Shanghai Key Laboratory for Antibody-Drug Conjugates with Innovative Target, National Key Laboratory of Innovative Immunotherapy, School of Chemistry and Chemical Engineering) B Bei Ding (Shanghai Key Laboratory for Antibody-Drug Conjugates with Innovative Target, National Key Laboratory of Innovative Immunotherapy, School of Chemistry and Chemical Engineering) F Farong Ye (Center for Chemical Glycobiology, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Zhangjiang Institute for Advanced Study, School of Pharmaceutical Sciences) P Ping Wang

Article Details

Volume / Issue Vol. 148, Issue 27
Published July 15, 2026
Pages 29391-29399
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (8)

J

Jianhui Yin

Shanghai Key Laboratory for Antibody-Drug Conjugates with Innovative Target, National Key Laboratory of Innovative Immunotherapy, School of Chemistry and Chemical Engineering

X

Xinliang Liu

Center for Chemical Glycobiology, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Zhangjiang Institute for Advanced Study, School of Pharmaceutical Sciences

Z

Zhe Meng

Shanghai Key Laboratory for Antibody-Drug Conjugates with Innovative Target, National Key Laboratory of Innovative Immunotherapy, School of Chemistry and Chemical Engineering

Y

Yixiang Shi

Center for Chemical Glycobiology, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Zhangjiang Institute for Advanced Study, School of Pharmaceutical Sciences

G

Guofeng Zhang

Shanghai Key Laboratory for Antibody-Drug Conjugates with Innovative Target, National Key Laboratory of Innovative Immunotherapy, School of Chemistry and Chemical Engineering

B

Bei Ding

Shanghai Key Laboratory for Antibody-Drug Conjugates with Innovative Target, National Key Laboratory of Innovative Immunotherapy, School of Chemistry and Chemical Engineering

F

Farong Ye

Center for Chemical Glycobiology, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, Zhangjiang Institute for Advanced Study, School of Pharmaceutical Sciences

P

Ping Wang