PROTAC-Mediated Degradation of mHTT Aggregates Attenuates Neurotoxicity in Cellular and R6/2 Mouse Models of Huntington’s Disease
P
Po-Chao Lu
(Institute of Chemistry)
Y
Yung-An Huang
(Institute of Chemistry)
N
Niaz Wali
(Institute of Chemistry)
M
Mei-Chun Tseng
(Institute of Chemistry)
R
Ruei-Yu He
(Institute of Chemistry)
Y
Yijuang Chern
(Institute of Biomedical Sciences)
T
Tzu-Tang Wei
(Department and Graduate Institute of Pharmacology, College of Medicine)
J
Jiun-Jie Shie
(Institute of Chemistry)
J
Joseph Jen-Tse Huang
(Institute of Chemistry)
Article Details
Volume / Issue
Vol. 148, Issue 8
Published
March 04, 2026
Pages
8107-8121
ISSN
0002-7863
Publisher
American Chemical Society
Journal Info
Journal of the American Chemical Society
American Chemical Society
ISSN: 0002-7863 Physical Sciences
Authors (9)
P
Po-Chao Lu
Institute of Chemistry
Y
Yung-An Huang
Institute of Chemistry
N
Niaz Wali
Institute of Chemistry
M
Mei-Chun Tseng
Institute of Chemistry
R
Ruei-Yu He
Institute of Chemistry
Y
Yijuang Chern
Institute of Biomedical Sciences
T
Tzu-Tang Wei
Department and Graduate Institute of Pharmacology, College of Medicine
J
Jiun-Jie Shie
Institute of Chemistry
J
Joseph Jen-Tse Huang
Institute of Chemistry
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