Programming One‐Dimensional Open‐Channel Superlattices with Edge‐Bonding of Meta‐DNA

Q Qin Xu L Le Li X Xiaoliang Chen (State Key Laboratory of Synergistic Chem-Bio Synthesis, State Key Laboratory of Micro-Nano Engineering Science, School of Chemistry and Chemical Engineering, New Cornerstone Science Laboratory, Frontiers Science Center for Transformative Molecules, Zhang Jiang Institute for Advanced Study and National Center for Translational Medicine) C Changmao Huang (Xi'an Key Laboratory of Functional Supramolecular Structure and Materials Key Laboratory of Synthetic and Natural Functional Molecule of Ministry of Education College of Chemistry & Materials Science Northwest University Xi'an Shaanxi 710127 China) J Jiangbo Liu (School of Chemistry and Chemical Engineering New Cornerstone Science Laboratory Frontiers Science Center for Transformative Molecules Zhangjiang Institute for Advanced Study and National Center for Translational Medicine Shanghai Jiao Tong University Shanghai 200240 China) W Wenhe Ma (State Key Laboratory of Synergistic Chem-Bio Synthesis, State Key Laboratory of Micro-Nano Engineering Science, School of Chemistry and Chemical Engineering, New Cornerstone Science Laboratory, Frontiers Science Center for Transformative Molecules, Zhang Jiang Institute for Advanced Study and National Center for Translational Medicine) M Meiyuan Qi (State Key Laboratory of Synergistic Chem-Bio Synthesis, State Key Laboratory of Micro-Nano Engineering Science, School of Chemistry and Chemical Engineering, New Cornerstone Science Laboratory, Frontiers Science Center for Transformative Molecules, Zhangjiang Institute for Advanced Study, and National Center for Translational Medicine) X Xiaolei Zuo (Institute of Molecular Medicine, Shanghai Key Laboratory for Nucleic Acids Chemistry and Nanomedicine, Renji Hospital, School of Medicine) X Xiaoguo Liu (State Key Laboratory of Synergistic Chem-Bio Synthesis, School of Chemistry and Chemical Engineering, New Cornerstone Science Laboratory, Frontiers Science Center for Transformative Molecules, Zhangjiang Institute for Advanced Study and National Center for Translational Medicine) M Mingqiang Li (State Key Laboratory of Synergistic Chem-Bio Synthesis, State Key Laboratory of Micro-Nano Engineering Science, School of Chemistry and Chemical Engineering, New Cornerstone Science Laboratory, Frontiers Science Center for Transformative Molecules, Zhangjiang Institute for Advanced Study, and National Center for Translational Medicine) X Xiangyuan Ouyang (Xi’an Key Laboratory of Functional Supramolecular Structure and Materials, Key Laboratory of Synthetic and Natural Functional Molecule of Ministry of Education, College of Chemistry and Materials Science) C Chunhai Fan (State Key Laboratory of Synergistic Chem-Bio Synthesis, School of Chemistry and Chemical Engineering, New Cornerstone Science Laboratory, Frontiers Science Center for Transformative Molecules, Zhang Jiang Institute for Advanced Study and National Center for Translational Medicine) G Guangbao Yao (State Key Laboratory of Synergistic Chem-Bio Synthesis, State Key Laboratory of Micro-Nano Engineering Science, School of Chemistry and Chemical Engineering, New Cornerstone Science Laboratory, Frontiers Science Center for Transformative Molecules, Zhangjiang Institute for Advanced Study, and National Center for Translational Medicine)

Abstract

Abstract The physicochemical properties of one‐dimensional (1D) porous nanomaterials are fundamentally influenced by their channel geometrical and topological characteristics. However, synthesis of geometrically and topologically diversified 1D porous crystals spanning the mesoporous‐to‐macroporous range remains a significant challenge. Here, we present a universal strategy for constructing 1D open‐channel superlattices through edge‐to‐edge assembly (edge‐bonding) of DNA‐sparsely modified meta‐DNA (M‐DNA). By programming the rigidity and length of sparsely distributed DNA bonds on M‐DNA surfaces, we achieved long‐range ordered assembly of triangular M‐DNA 1D single‐channel superlattice (3.7 ± 1.2 µm) with a macroporous structure. The generality of this approach was further demonstrated by assembling hexagonal M‐DNA into 1D multi‐channel superlattice (3.6 ± 1.0 µm) with a mesoporous structure, thereby reducing the pore size from 140 to 29 nm and the porosity from ∼94.2 to ∼87.5%. Furthermore, an ultrathin gold layer grown on the triangular M‐DNA superlattice exhibited a ∼3.3‐fold enhancement in electrocatalytic activity compared to non‐assembled triangular M‐DNA, attributed to the increased surface area and narrower bandgap. This work broadens the design framework for porous crystals assembled via DNA nanotechnology and highlights their potential applications in catalysis, energy conversion, and beyond.

Article Details

Volume / Issue Vol. 64, Issue 28
Published July 07, 2025
ISSN 1433-7851
Publisher Wiley

Journal Info

Angewandte Chemie International Edition

Wiley

ISSN: 1433-7851 Physical Sciences

Authors (13)

Q

Qin Xu

L

Le Li

X

Xiaoliang Chen

State Key Laboratory of Synergistic Chem-Bio Synthesis, State Key Laboratory of Micro-Nano Engineering Science, School of Chemistry and Chemical Engineering, New Cornerstone Science Laboratory, Frontiers Science Center for Transformative Molecules, Zhang Jiang Institute for Advanced Study and National Center for Translational Medicine

C

Changmao Huang

Xi'an Key Laboratory of Functional Supramolecular Structure and Materials Key Laboratory of Synthetic and Natural Functional Molecule of Ministry of Education College of Chemistry & Materials Science Northwest University Xi'an Shaanxi 710127 China

J

Jiangbo Liu

School of Chemistry and Chemical Engineering New Cornerstone Science Laboratory Frontiers Science Center for Transformative Molecules Zhangjiang Institute for Advanced Study and National Center for Translational Medicine Shanghai Jiao Tong University Shanghai 200240 China

W

Wenhe Ma

State Key Laboratory of Synergistic Chem-Bio Synthesis, State Key Laboratory of Micro-Nano Engineering Science, School of Chemistry and Chemical Engineering, New Cornerstone Science Laboratory, Frontiers Science Center for Transformative Molecules, Zhang Jiang Institute for Advanced Study and National Center for Translational Medicine

M

Meiyuan Qi

State Key Laboratory of Synergistic Chem-Bio Synthesis, State Key Laboratory of Micro-Nano Engineering Science, School of Chemistry and Chemical Engineering, New Cornerstone Science Laboratory, Frontiers Science Center for Transformative Molecules, Zhangjiang Institute for Advanced Study, and National Center for Translational Medicine

X

Xiaolei Zuo

Institute of Molecular Medicine, Shanghai Key Laboratory for Nucleic Acids Chemistry and Nanomedicine, Renji Hospital, School of Medicine

X

Xiaoguo Liu

State Key Laboratory of Synergistic Chem-Bio Synthesis, School of Chemistry and Chemical Engineering, New Cornerstone Science Laboratory, Frontiers Science Center for Transformative Molecules, Zhangjiang Institute for Advanced Study and National Center for Translational Medicine

M

Mingqiang Li

State Key Laboratory of Synergistic Chem-Bio Synthesis, State Key Laboratory of Micro-Nano Engineering Science, School of Chemistry and Chemical Engineering, New Cornerstone Science Laboratory, Frontiers Science Center for Transformative Molecules, Zhangjiang Institute for Advanced Study, and National Center for Translational Medicine

X

Xiangyuan Ouyang

Xi’an Key Laboratory of Functional Supramolecular Structure and Materials, Key Laboratory of Synthetic and Natural Functional Molecule of Ministry of Education, College of Chemistry and Materials Science

C

Chunhai Fan

State Key Laboratory of Synergistic Chem-Bio Synthesis, School of Chemistry and Chemical Engineering, New Cornerstone Science Laboratory, Frontiers Science Center for Transformative Molecules, Zhang Jiang Institute for Advanced Study and National Center for Translational Medicine

G

Guangbao Yao

State Key Laboratory of Synergistic Chem-Bio Synthesis, State Key Laboratory of Micro-Nano Engineering Science, School of Chemistry and Chemical Engineering, New Cornerstone Science Laboratory, Frontiers Science Center for Transformative Molecules, Zhangjiang Institute for Advanced Study, and National Center for Translational Medicine