Programmable targeted RNA degradation via dCas13d-directed chaperone-mediated autophagy (dCasCMA)

H Hui-Ping Wen C Cong Yu (State Key Laboratory of Medicinal Chemical Biology, Frontiers Science Centre for New Organic Matter, Tianjin Key Laboratory of Biosensing and Molecular Recognition, Research Center for Analytical Sciences, College of Chemistry, School of Medicine, and Frontiers Science Centre for Cell Responses) S Shuli Bi L Lin-Han Jiang Z Zhi-Gang Wang (State Key Laboratory of Medicinal Chemical Biology, Frontiers Science Centre for New Organic Matter, Tianjin Key Laboratory of Biosensing and Molecular Recognition, Research Centre for Analytical Sciences, College of Chemistry, School of Medicine, and Frontiers Science Centre for Cell Responses) Z Zhuhua Yao (Department of Cardiology, Tianjin Union Medical Center) D Dai-Wen Pang S Shu-Lin Liu (State Key Laboratory of Medicinal Chemical Biology, Frontiers Science Centre for New Organic Matter, Tianjin Key Laboratory of Biosensing and Molecular Recognition, Research Centre for Analytical Sciences, College of Chemistry, School of Medicine, and Frontiers Science Centre for Cell Responses)

Article Details

Volume / Issue Vol. 16, Issue 1
Published November 28, 2025
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (8)

H

Hui-Ping Wen

C

Cong Yu

State Key Laboratory of Medicinal Chemical Biology, Frontiers Science Centre for New Organic Matter, Tianjin Key Laboratory of Biosensing and Molecular Recognition, Research Center for Analytical Sciences, College of Chemistry, School of Medicine, and Frontiers Science Centre for Cell Responses

S

Shuli Bi

L

Lin-Han Jiang

Z

Zhi-Gang Wang

State Key Laboratory of Medicinal Chemical Biology, Frontiers Science Centre for New Organic Matter, Tianjin Key Laboratory of Biosensing and Molecular Recognition, Research Centre for Analytical Sciences, College of Chemistry, School of Medicine, and Frontiers Science Centre for Cell Responses

Z

Zhuhua Yao

Department of Cardiology, Tianjin Union Medical Center

D

Dai-Wen Pang

S

Shu-Lin Liu

State Key Laboratory of Medicinal Chemical Biology, Frontiers Science Centre for New Organic Matter, Tianjin Key Laboratory of Biosensing and Molecular Recognition, Research Centre for Analytical Sciences, College of Chemistry, School of Medicine, and Frontiers Science Centre for Cell Responses