Prime Editing for p47 <sup>phox</sup> -Deficient Chronic Granulomatous Disease

J Jennifer L. Gori (Prime Medicine, Cambridge, MA) E Elie Haddad (Department of Pediatrics, CHU Sainte-Justine Azrieli Research Center, Université de Montréal, Montreal) H Haydar Frangoul (Sarah Cannon Research Institute at the Children’s Hospital at TriStar Centennial, Nashville) D Donald B. Kohn (Department of Pediatrics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles) E Emma C. Morris (National Institute for Health and Care Research, University College London Hospitals Biomedical Research Centre, London) B Bradley N. Martin (Prime Medicine, Cambridge, MA) B Briana A. Deary (Prime Medicine, Cambridge, MA) M McKinley Nickerson (Prime Medicine, Cambridge, MA) R Rebecca L. Scholz (Prime Medicine, Cambridge, MA) I Isabel Fernandez (Department of Pediatrics, CHU Sainte-Justine Azrieli Research Center, Université de Montréal, Montreal) K Karine Leveille (Department of Pediatrics, CHU Sainte-Justine Azrieli Research Center, Université de Montréal, Montreal) S Suk See De Ravin E Elizabeth M. Kang (Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD) M Marie Pierzynski (Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD) T Tyra Estwick (Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD) P Patricia Littel (Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD) D Douglas B. Kuhns (Frederick National Laboratory for Cancer Research, Frederick, MD) D Debra A. Long Priel (Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD) P Pierre Teira (Department of Pediatrics, CHU Sainte-Justine Azrieli Research Center, Université de Montréal, Montreal) S Stuart Turvey (Department of Microbiology and Immunology, University of British Columbia) J Jordyn Arnold (Department of Pediatrics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles) M Misty D. Evans (Sarah Cannon Research Institute, Children’s Hospital at TriStar Centennial, Nashville) M Meghann McManus (Sarah Cannon Research Institute, Nashville) B Ben Carpenter (Department of Hematology, University College London Hospitals NHS Foundation Trust, London) D David P. Waterman (Prime Medicine, Cambridge, MA) A Andrew V. Anzalone (Prime Medicine, Cambridge, MA) A Alexandria Petrusich (Prime Medicine, Cambridge, MA) C Christa E. Osuna (Prime Medicine, Cambridge, MA) T Tiernan T. O’Malley (Prime Medicine, Cambridge, MA) J Jacob Stewart-Ornstein (Prime Medicine, Cambridge, MA) J Jack M. Heath (Prime Medicine, Cambridge, MA) B Barrett J. Nehilla (Prime Medicine, Cambridge, MA) M Mohammed Asmal (Prime Medicine, Cambridge, MA) H Harry L. Malech (Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD)

Article Details

Volume / Issue Vol. 394, Issue 12
Published March 26, 2026
Pages 1195-1203
ISSN 0028-4793
Publisher Massachusetts Medical Society

Journal Info

New England Journal of Medicine

Massachusetts Medical Society

ISSN: 0028-4793 Social Sciences

Authors (34)

J

Jennifer L. Gori

Prime Medicine, Cambridge, MA

E

Elie Haddad

Department of Pediatrics, CHU Sainte-Justine Azrieli Research Center, Université de Montréal, Montreal

H

Haydar Frangoul

Sarah Cannon Research Institute at the Children’s Hospital at TriStar Centennial, Nashville

D

Donald B. Kohn

Department of Pediatrics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles

E

Emma C. Morris

National Institute for Health and Care Research, University College London Hospitals Biomedical Research Centre, London

B

Bradley N. Martin

Prime Medicine, Cambridge, MA

B

Briana A. Deary

Prime Medicine, Cambridge, MA

M

McKinley Nickerson

Prime Medicine, Cambridge, MA

R

Rebecca L. Scholz

Prime Medicine, Cambridge, MA

I

Isabel Fernandez

Department of Pediatrics, CHU Sainte-Justine Azrieli Research Center, Université de Montréal, Montreal

K

Karine Leveille

Department of Pediatrics, CHU Sainte-Justine Azrieli Research Center, Université de Montréal, Montreal

S

Suk See De Ravin

E

Elizabeth M. Kang

Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD

M

Marie Pierzynski

Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD

T

Tyra Estwick

Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD

P

Patricia Littel

Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD

D

Douglas B. Kuhns

Frederick National Laboratory for Cancer Research, Frederick, MD

D

Debra A. Long Priel

Leidos Biomedical Research, Frederick National Laboratory for Cancer Research, Frederick, MD

P

Pierre Teira

Department of Pediatrics, CHU Sainte-Justine Azrieli Research Center, Université de Montréal, Montreal

S

Stuart Turvey

Department of Microbiology and Immunology, University of British Columbia

J

Jordyn Arnold

Department of Pediatrics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles

M

Misty D. Evans

Sarah Cannon Research Institute, Children’s Hospital at TriStar Centennial, Nashville

M

Meghann McManus

Sarah Cannon Research Institute, Nashville

B

Ben Carpenter

Department of Hematology, University College London Hospitals NHS Foundation Trust, London

D

David P. Waterman

Prime Medicine, Cambridge, MA

A

Andrew V. Anzalone

Prime Medicine, Cambridge, MA

A

Alexandria Petrusich

Prime Medicine, Cambridge, MA

C

Christa E. Osuna

Prime Medicine, Cambridge, MA

T

Tiernan T. O’Malley

Prime Medicine, Cambridge, MA

J

Jacob Stewart-Ornstein

Prime Medicine, Cambridge, MA

J

Jack M. Heath

Prime Medicine, Cambridge, MA

B

Barrett J. Nehilla

Prime Medicine, Cambridge, MA

M

Mohammed Asmal

Prime Medicine, Cambridge, MA

H

Harry L. Malech

Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD