Journal of the American Chemical Society

Precursors of Carboximidates Deriving from Thioamide-Trimethyl-Lock System: A General Method for Designing Stable Cascade Acid-Sensitive Prodrugs

J Jianru Liu (State Key Laboratory of Natural Medicines, Center of Drug Discovery) Y Yuanan Wang (Center of Drug Discovery, State Key Laboratory of Natural Medicine) Q Qiwei Zhou (School of Science) W Wen Peng (State Key Laboratory of Natural Medicines, Center of Drug Discovery) P Peiyuan Li (Mudi Meng Honors College) C Chao Ban (School of Science) Y Yangyin Xue (State Key Laboratory of Natural Medicines, Center of Drug Discovery) Y Yan Liang (State Key Laboratory of Fine Chemicals, School of Chemistry) Z Zhongbo Wang (State Key Laboratory of Natural Medicines, Key Laboratory of Drug Metabolism and Pharmacokinetics) H Hao Hao (State Key Laboratory of Natural Medicines, Key Laboratory of Drug Metabolism and Pharmacokinetics) Y Yanzhao Chen (Center of Drug Discovery, State Key Laboratory of Natural Medicine) W Weiwei Guo (Center of Drug Discovery, State Key Laboratory of Natural Medicine) Y Yueqin Zheng (Center of Drug Discovery, State Key Laboratory of Natural Medicine)
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Article Details

Volume / Issue Vol. 147, Issue 27
Published July 09, 2025
Pages 23583-23593
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society
ISSN: 0002-7863 Physical Sciences

Authors (13)

J

Jianru Liu

State Key Laboratory of Natural Medicines, Center of Drug Discovery

Y

Yuanan Wang

Center of Drug Discovery, State Key Laboratory of Natural Medicine

Q

Qiwei Zhou

School of Science

W

Wen Peng

State Key Laboratory of Natural Medicines, Center of Drug Discovery

P

Peiyuan Li

Mudi Meng Honors College

C

Chao Ban

School of Science

Y

Yangyin Xue

State Key Laboratory of Natural Medicines, Center of Drug Discovery

Y

Yan Liang

State Key Laboratory of Fine Chemicals, School of Chemistry

Z

Zhongbo Wang

State Key Laboratory of Natural Medicines, Key Laboratory of Drug Metabolism and Pharmacokinetics

H

Hao Hao

State Key Laboratory of Natural Medicines, Key Laboratory of Drug Metabolism and Pharmacokinetics

Y

Yanzhao Chen

Center of Drug Discovery, State Key Laboratory of Natural Medicine

W

Weiwei Guo

Center of Drug Discovery, State Key Laboratory of Natural Medicine

Y

Yueqin Zheng

Center of Drug Discovery, State Key Laboratory of Natural Medicine

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