Nature Communications

PRDX1 promotes testosterone synthesis and attenuates aging via redox regulation of ATG4B to modulate lipophagy

H Hanbin Zhang K Ke Ma Y Yuge Zhuang X Xixian Cen X Xiaoyuan Zhang (Key Laboratory for Soft Chemistry and Functional Materials of Ministry Education, School of Chemistry and Chemical Engineering) S Shipeng Ruan H Hongrui Feng R Runduan Yi Z Zicong Huang C Chuyu Huang M Minyu Xie L Lan Tang (Department of Anesthesiology, The First Affiliated Hospital of University of Science and Technology of China, Center for Advance Interdisciplinary Science and Biomedicine of Institute of Health and Medicine, Hefei National Laboratory for Physical Sciences at the Microscale, Division of Life Sciences and Medicine, University of Science and Technology of China) X Xiong Cao G Guofei Zhang X Xiangjin Kang Y Yong Fan (Center for AI and Data Science for Integrated Diagnostics, Perelman School of Medicine, University of Pennsylvania) Z Zhenguo Chen
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Article Details

Volume / Issue Vol. 16, Issue 1
Published November 19, 2025
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio
ISSN: 2041-1723 Open Access Life Sciences

Authors (17)

H

Hanbin Zhang

K

Ke Ma

Y

Yuge Zhuang

X

Xixian Cen

X

Xiaoyuan Zhang

Key Laboratory for Soft Chemistry and Functional Materials of Ministry Education, School of Chemistry and Chemical Engineering

S

Shipeng Ruan

H

Hongrui Feng

R

Runduan Yi

Z

Zicong Huang

C

Chuyu Huang

M

Minyu Xie

L

Lan Tang

Department of Anesthesiology, The First Affiliated Hospital of University of Science and Technology of China, Center for Advance Interdisciplinary Science and Biomedicine of Institute of Health and Medicine, Hefei National Laboratory for Physical Sciences at the Microscale, Division of Life Sciences and Medicine, University of Science and Technology of China

X

Xiong Cao

G

Guofei Zhang

X

Xiangjin Kang

Y

Yong Fan

Center for AI and Data Science for Integrated Diagnostics, Perelman School of Medicine, University of Pennsylvania

Z

Zhenguo Chen

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