PPARα-mediated lipid metabolism reprogramming supports anti-EGFR therapy resistance in head and neck squamous cell carcinoma

Valentin Van den bossche; Julie Vignau; Engy Vigneron; Isabella Rizzi; Hannah Zaryouh; An Wouters; Jérôme Ambroise; Steven Van Laere; Simon Beyaert; Raphaël Helaers; Cédric van Marcke; Lionel Mignion; Elise Y. Lepicard; Bénédicte F. Jordan; Céline Guilbaud; Olivier Lowyck; Hajar Dahou; Antonella Mendola; Manon Desgres; Léo Aubert; Isabelle Gerin; Guido T. Bommer; Romain Boidot; Perrine Vermonden; Aurélien Warnant; Yvan Larondelle; Jean-Pascal Machiels; Olivier Feron; Sandra Schmitz; Cyril Corbet

doi:10.1038/s41467-025-56675-3

PPARα-mediated lipid metabolism reprogramming supports anti-EGFR therapy resistance in head and neck squamous cell carcinoma

V Valentin Van den bossche J Julie Vignau E Engy Vigneron I Isabella Rizzi H Hannah Zaryouh A An Wouters J Jérôme Ambroise S Steven Van Laere S Simon Beyaert R Raphaël Helaers C Cédric van Marcke L Lionel Mignion E Elise Y. Lepicard B Bénédicte F. Jordan C Céline Guilbaud O Olivier Lowyck H Hajar Dahou A Antonella Mendola M Manon Desgres L Léo Aubert I Isabelle Gerin G Guido T. Bommer R Romain Boidot P Perrine Vermonden A Aurélien Warnant Y Yvan Larondelle J Jean-Pascal Machiels O Olivier Feron S Sandra Schmitz C Cyril Corbet

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Article Details

Journal Nature Communications

Volume / Issue Vol. 16, Issue 1

Published February 01, 2025

DOI 10.1038/s41467-025-56675-3

ISSN 2041-1723

Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (30)

V

Valentin Van den bossche

J

Julie Vignau

E

Engy Vigneron

I

Isabella Rizzi

H

Hannah Zaryouh

A

An Wouters

J

Jérôme Ambroise

S

Steven Van Laere

S

Simon Beyaert

R

Raphaël Helaers

C

Cédric van Marcke

L

Lionel Mignion

E

Elise Y. Lepicard

B

Bénédicte F. Jordan

C

Céline Guilbaud

O

Olivier Lowyck

H

Hajar Dahou

A

Antonella Mendola

M

Manon Desgres

L

Léo Aubert

I

Isabelle Gerin

G

Guido T. Bommer

R

Romain Boidot

P

Perrine Vermonden

A

Aurélien Warnant

Y

Yvan Larondelle

J

Jean-Pascal Machiels

O

Olivier Feron

S

Sandra Schmitz

C

Cyril Corbet

PPARα-mediated lipid metabolism reprogramming supports anti-EGFR therapy resistance in head and neck squamous cell carcinoma

Article Details

Journal Info

Authors (30)

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