Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism (Adv. Mater. 22/2026)

Ashish Sarode; Christian Ortiz; Tadeh Derstepanian; Natalia Vargas‐Montoya; Priyal Patel; Nikita Khadse; Saikat Manna; Ryan Landis; Joseph Skaleski; Lianne Boeglin; Hongfeng Deng; Anusha Dias; Hong Wang; Debora Barreiros Petropolis; Barak Yahalom; Shrirang Karve; Frank DeRosa

doi:10.1002/adma.73003

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism (Adv. Mater. 22/2026)

A Ashish Sarode (mRNA Center of Excellence Sanofi Waltham MA 02451 USA) C Christian Ortiz (mRNA Center of Excellence Sanofi Waltham MA 02451 USA) T Tadeh Derstepanian (mRNA Center of Excellence Sanofi Waltham MA 02451 USA) N Natalia Vargas‐Montoya (mRNA Center of Excellence Sanofi Waltham MA 02451 USA) P Priyal Patel (mRNA Center of Excellence Sanofi Waltham MA 02451 USA) N Nikita Khadse (mRNA Center of Excellence Sanofi Waltham MA 02451 USA) S Saikat Manna (mRNA Center of Excellence Sanofi Waltham MA 02451 USA) R Ryan Landis (mRNA Center of Excellence Sanofi Waltham MA 02451 USA) J Joseph Skaleski (mRNA Center of Excellence Sanofi Waltham MA 02451 USA) L Lianne Boeglin (mRNA Center of Excellence Sanofi Waltham MA 02451 USA) H Hongfeng Deng (mRNA Center of Excellence Sanofi Waltham MA 02451 USA) A Anusha Dias (mRNA Center of Excellence Sanofi Waltham MA 02451 USA) H Hong Wang D Debora Barreiros Petropolis (Genomic Medicine Unit Sanofi Waltham MA 02451 USA) B Barak Yahalom (Alpha Preclinical 200 Westboro Road, North Grafton Worcester MA 01536 USA) S Shrirang Karve (mRNA Center of Excellence Sanofi Waltham MA 02451 USA) F Frank DeRosa (mRNA Center of Excellence Sanofi Waltham MA 02451 USA)

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Article Details

Journal Advanced Materials

Volume / Issue Vol. 38, Issue 22

Published April 01, 2026

DOI 10.1002/adma.73003

ISSN 0935-9648

Publisher Unknown Publisher

Journal Info

Advanced Materials

Unknown Publisher

ISSN: 0935-9648 Physical Sciences

Authors (17)

A

Ashish Sarode

mRNA Center of Excellence Sanofi Waltham MA 02451 USA

C

Christian Ortiz

mRNA Center of Excellence Sanofi Waltham MA 02451 USA

T

Tadeh Derstepanian

mRNA Center of Excellence Sanofi Waltham MA 02451 USA

N

Natalia Vargas‐Montoya

mRNA Center of Excellence Sanofi Waltham MA 02451 USA

P

Priyal Patel

mRNA Center of Excellence Sanofi Waltham MA 02451 USA

N

Nikita Khadse

mRNA Center of Excellence Sanofi Waltham MA 02451 USA

S

Saikat Manna

mRNA Center of Excellence Sanofi Waltham MA 02451 USA

R

Ryan Landis

mRNA Center of Excellence Sanofi Waltham MA 02451 USA

J

Joseph Skaleski

mRNA Center of Excellence Sanofi Waltham MA 02451 USA

L

Lianne Boeglin

mRNA Center of Excellence Sanofi Waltham MA 02451 USA

H

Hongfeng Deng

mRNA Center of Excellence Sanofi Waltham MA 02451 USA

A

Anusha Dias

mRNA Center of Excellence Sanofi Waltham MA 02451 USA

H

Hong Wang

D

Debora Barreiros Petropolis

Genomic Medicine Unit Sanofi Waltham MA 02451 USA

B

Barak Yahalom

Alpha Preclinical 200 Westboro Road, North Grafton Worcester MA 01536 USA

S

Shrirang Karve

mRNA Center of Excellence Sanofi Waltham MA 02451 USA

F

Frank DeRosa

mRNA Center of Excellence Sanofi Waltham MA 02451 USA

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism (Adv. Mater. 22/2026)

Article Details

Journal Info

Authors (17)

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