POLY-Senolytic nanoplatform for tumor-specific eradication of senescent tumor cells and mitigation of radiotherapy-induced immune resistance of cancer

Y Yi Lai (State Key Laboratory of Chemical Biology and Center of Pharmaceutics, Shanghai Institute of Materia Medica) S Shunan Zhang (Institute of Carbon Neutrality) J Jiaxing Pan (State Key Laboratory of Chemical Biology and Center of Pharmaceutics, Shanghai Institute of Materia Medica) W Wenyue Lan M Min Li Z Zifan Zhu (School of Chemistry and Molecular Engineering) L Leiming Xu B Bruno G. De Geest (Department of Pharmaceutics) T Twan Lammers (Institute for Experimental Molecular Imaging) W Wen Zhang H Haijun Yu (State Key Laboratory of Chemical Biology and Center of Pharmaceutics, Shanghai Institute of Materia Medica) Z Zhiai Xu (School of Chemistry and Molecular Engineering)

Article Details

Volume / Issue Vol. 17, Issue 1
Published June 18, 2026
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (12)

Y

Yi Lai

State Key Laboratory of Chemical Biology and Center of Pharmaceutics, Shanghai Institute of Materia Medica

S

Shunan Zhang

Institute of Carbon Neutrality

J

Jiaxing Pan

State Key Laboratory of Chemical Biology and Center of Pharmaceutics, Shanghai Institute of Materia Medica

W

Wenyue Lan

M

Min Li

Z

Zifan Zhu

School of Chemistry and Molecular Engineering

L

Leiming Xu

B

Bruno G. De Geest

Department of Pharmaceutics

T

Twan Lammers

Institute for Experimental Molecular Imaging

W

Wen Zhang

H

Haijun Yu

State Key Laboratory of Chemical Biology and Center of Pharmaceutics, Shanghai Institute of Materia Medica

Z

Zhiai Xu

School of Chemistry and Molecular Engineering