Photoswitchable RNA Degraders for Spatiotemporal Activation of Host-Directed Antivirals in Mammalian Cells

M Moritz Fink (Department of Chemistry and Applied Biosciences, Laboratory of Organic Chemistry) S Susanne Wolfrum (Laboratorium für Organische Chemie, D-CHAB, ETH Zürich, Vladimir-Prelog-Weg 3, 8093 Zürich, Switzerland) R Reto Lang (Institute of Virology and Immunology, Bern and Mittelhäusern) V Volker Thiel (Institute of Virology and Immunology, Bern and Mittelhäusern) E Erick M. Carreira (Laboratory of Organic Chemistry, Department of Chemistry and Applied Biosciences)

Article Details

Volume / Issue Vol. 147, Issue 45
Published November 12, 2025
Pages 41717-41726
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (5)

M

Moritz Fink

Department of Chemistry and Applied Biosciences, Laboratory of Organic Chemistry

S

Susanne Wolfrum

Laboratorium für Organische Chemie, D-CHAB, ETH Zürich, Vladimir-Prelog-Weg 3, 8093 Zürich, Switzerland

R

Reto Lang

Institute of Virology and Immunology, Bern and Mittelhäusern

V

Volker Thiel

Institute of Virology and Immunology, Bern and Mittelhäusern

E

Erick M. Carreira

Laboratory of Organic Chemistry, Department of Chemistry and Applied Biosciences