Photocontrolled trimethoprim PROTACs targeting the eDHFR protein tag

Nitika Sharma; Swarbhanu Sarkar; Tongil Ko; Kimberly J. Edwards; Jonathan M. Pham; Tommy Nguyen; Angela Z. Gong; Joseph Flores; Dirk Trauner; Mark A. Sellmyer

doi:10.1038/s41467-025-67527-5

Photocontrolled trimethoprim PROTACs targeting the eDHFR protein tag

N Nitika Sharma S Swarbhanu Sarkar T Tongil Ko K Kimberly J. Edwards J Jonathan M. Pham T Tommy Nguyen A Angela Z. Gong J Joseph Flores D Dirk Trauner (P. Roy and Diana T. Vagelos Laboratories, Department of Chemistry) M Mark A. Sellmyer

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Article Details

Journal Nature Communications

Volume / Issue Vol. 17, Issue 1

Published December 27, 2025

DOI 10.1038/s41467-025-67527-5

ISSN 2041-1723

Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (10)

N

Nitika Sharma

S

Swarbhanu Sarkar

T

Tongil Ko

K

Kimberly J. Edwards

J

Jonathan M. Pham

T

Tommy Nguyen

A

Angela Z. Gong

J

Joseph Flores

D

Dirk Trauner

P. Roy and Diana T. Vagelos Laboratories, Department of Chemistry

M

Mark A. Sellmyer

Photocontrolled trimethoprim PROTACs targeting the eDHFR protein tag

Article Details

Journal Info

Authors (10)

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