Photobiocatalytic Enantioselective Benzylic C(sp
                    <sup>3</sup>
                    )–H Acylation Enabled by Thiamine-Dependent Enzymes via Intermolecular Hydrogen Atom Transfer

Yen-Chu Lu; Ronald D. Adukure; Satyajit Roy; Derek L. Chien; Matthew J. McGill; Sarthi Polara; G. Andrés Cisneros; Karl A. Scheidt; Rudi Fasan

doi:10.1021/jacs.5c01642

Journal of the American Chemical Society

Photobiocatalytic Enantioselective Benzylic C(sp <sup>3</sup> )–H Acylation Enabled by Thiamine-Dependent Enzymes via Intermolecular Hydrogen Atom Transfer

Y Yen-Chu Lu (Department of Chemistry and Biochemistry) R Ronald D. Adukure (Department of Chemistry and Biochemistry) S Satyajit Roy (Department of Chemistry and Biochemistry, The University of Texas at Dallas, 800 W. Campbell Road, Richardson, Texas 75080, United States) D Derek L. Chien (Department of Chemistry) M Matthew J. McGill (Department of Chemistry) S Sarthi Polara (Department of Chemistry and Biochemistry) G G. Andrés Cisneros (Department of Chemistry and Biochemistry) K Karl A. Scheidt (Department of Chemistry) R Rudi Fasan

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Article Details

Journal Journal of the American Chemical Society

Volume / Issue Vol. 147, Issue 21

Published May 28, 2025

Pages 17804-17816

DOI 10.1021/jacs.5c01642

ISSN 0002-7863

Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (9)

Y

Yen-Chu Lu

Department of Chemistry and Biochemistry

R

Ronald D. Adukure

Department of Chemistry and Biochemistry

S

Satyajit Roy

Department of Chemistry and Biochemistry, The University of Texas at Dallas, 800 W. Campbell Road, Richardson, Texas 75080, United States

D

Derek L. Chien

Department of Chemistry

M

Matthew J. McGill

Department of Chemistry

S

Sarthi Polara

Department of Chemistry and Biochemistry

G

G. Andrés Cisneros

Department of Chemistry and Biochemistry

K

Karl A. Scheidt

Department of Chemistry

R

Rudi Fasan

Photobiocatalytic Enantioselective Benzylic C(sp <sup>3</sup> )–H Acylation Enabled by Thiamine-Dependent Enzymes via Intermolecular Hydrogen Atom Transfer

Article Details

Journal Info

Authors (9)

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