Phenotyping by Molecular Mobility: Low-Affinity Reversible Probes Enable Characterizing and Classifying Cells Populations by Single-Molecule Imaging

R Roger Riera (Department of Biomedical Engineering, Institute for Complex Molecular Systems (ICMS), Eindhoven University of Technology, De Zaale, Eindhoven 5612AZ, The Netherlands) L Laurence W. Fitzpatrick (Department of Biomedical Engineering, Institute for Complex Molecular Systems (ICMS), Eindhoven University of Technology, De Zaale, Eindhoven 5612AZ, The Netherlands) S Simon Huet (Affilogic, 24 rue de la Rainière, Nantes 44300, France) M Marrit M.E. Tholen (Department of Biomedical Engineering, Institute for Complex Molecular Systems (ICMS), Eindhoven University of Technology, De Zaale, Eindhoven 5612AZ, The Netherlands) P Perrine Jacquot (Affilogic, 24 rue de la Rainière, Nantes 44300, France) M Mathieu Cinier (Affilogic, 24 rue de la Rainière, Nantes 44300, France) L Laura Woythe (Department of Biomedical Engineering, Institute for Complex Molecular Systems (ICMS), Eindhoven University of Technology, De Zaale, Eindhoven 5612AZ, The Netherlands) M Marine Tanou (Affilogic, 24 rue de la Rainière, Nantes 44300, France) C Cristina Izquierdo-Lozano (Department of Biomedical Engineering, Institute for Complex Molecular Systems (ICMS), Eindhoven University of Technology, De Zaale, Eindhoven 5612AZ, The Netherlands) M Mats Verhoeven (Department of Biomedical Engineering, Institute for Complex Molecular Systems (ICMS), Eindhoven University of Technology, De Zaale, Eindhoven 5612AZ, The Netherlands) L Lorenzo Albertazzi (Department of Biomedical Engineering, Institute for Complex Molecular Systems (ICMS), Eindhoven University of Technology, De Zaale, Eindhoven 5612AZ, The Netherlands)

Article Details

Volume / Issue Vol. 148, Issue 12
Published April 01, 2026
Pages 12565-12575
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (11)

R

Roger Riera

Department of Biomedical Engineering, Institute for Complex Molecular Systems (ICMS), Eindhoven University of Technology, De Zaale, Eindhoven 5612AZ, The Netherlands

L

Laurence W. Fitzpatrick

Department of Biomedical Engineering, Institute for Complex Molecular Systems (ICMS), Eindhoven University of Technology, De Zaale, Eindhoven 5612AZ, The Netherlands

S

Simon Huet

Affilogic, 24 rue de la Rainière, Nantes 44300, France

M

Marrit M.E. Tholen

Department of Biomedical Engineering, Institute for Complex Molecular Systems (ICMS), Eindhoven University of Technology, De Zaale, Eindhoven 5612AZ, The Netherlands

P

Perrine Jacquot

Affilogic, 24 rue de la Rainière, Nantes 44300, France

M

Mathieu Cinier

Affilogic, 24 rue de la Rainière, Nantes 44300, France

L

Laura Woythe

Department of Biomedical Engineering, Institute for Complex Molecular Systems (ICMS), Eindhoven University of Technology, De Zaale, Eindhoven 5612AZ, The Netherlands

M

Marine Tanou

Affilogic, 24 rue de la Rainière, Nantes 44300, France

C

Cristina Izquierdo-Lozano

Department of Biomedical Engineering, Institute for Complex Molecular Systems (ICMS), Eindhoven University of Technology, De Zaale, Eindhoven 5612AZ, The Netherlands

M

Mats Verhoeven

Department of Biomedical Engineering, Institute for Complex Molecular Systems (ICMS), Eindhoven University of Technology, De Zaale, Eindhoven 5612AZ, The Netherlands

L

Lorenzo Albertazzi

Department of Biomedical Engineering, Institute for Complex Molecular Systems (ICMS), Eindhoven University of Technology, De Zaale, Eindhoven 5612AZ, The Netherlands