PFAS-contaminated drinking water harms infants

R Robert Baluja (Cornerstone Research) B Bo Guo (Department of Hydrology and Atmospheric Sciences) W Wesley Howden (Private address) A Ashley Langer (Department of Economics) D Derek Lemoine (Department of Economics)

Abstract

There is evidence of widespread human exposure to per- and polyfluoroalkyl substances (PFAS) but limited evidence of the human health impacts of this exposure. Using data on New Hampshire births from 2010–2019, we show that mothers receiving water that had flowed beneath a PFAS-contaminated site, as opposed to comparable mothers receiving water that had flowed toward a PFAS-contaminated site, had 191% [95% CI: 83–298%] higher first-year infant mortality (611 [268–955] additional first-year deaths per 100k births); 168% [42–294%] more births before 28 wk of gestational age (466 [116–817] additional such births per 100k births); and 180% [57–302%] more births with weight below 1,000 g (607 [192–1022] additional such births per 100k births). Extrapolating to the contiguous U.S., PFAS contamination imposes annual social costs of approximately $8 billion. These health costs are substantially larger than current outside estimates of the cost of removing PFAS from the public water supply.

Article Details

Volume / Issue Vol. 122, Issue 50
Published December 16, 2025
ISSN 0027-8424
Publisher National Academy of Sciences

Authors (5)

R

Robert Baluja

Cornerstone Research

B

Bo Guo

Department of Hydrology and Atmospheric Sciences

W

Wesley Howden

Private address

A

Ashley Langer

Department of Economics

D

Derek Lemoine

Department of Economics