Pediatric Life Support: 2025 International Liaison Committee on Resuscitation Consensus on Science With Treatment Recommendations

B Barnaby R. Scholefield J Jason Acworth K Kee-Chong Ng L Lokesh Kumar Tiwari T Tia T. Raymond A Andrea Christoff S Stephan Katzenschlager R Raffo Escalante-Kanashiro A Arun Bansal A Alexis Topjian (Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States) M Monica Kleinman H Hiroshi Kurosawa M Michelle C. Myburgh J Jimena del Castillo J Joseph Rossano J Jana Djakow A Anne-Marie Guerguerian (The Hospital for Sick Children, Toronto, Ontario, Canada) V Vinay M. Nadkarni T Thomaz Bittencourt Couto S Stephen M. Schexnayder G Gabrielle Nuthall J Janice A. Tijssen G Gene Yong-Kwang Ong J James M. Gray J Jesus López-Herce E Ester Shambekela Ambunda J Jerry P. Nolan (From the Warwick Medical School, Clinical Trials Unit, University of Warwick (K.C., C.J., J.P.N., J.B.L., J.M.M., F.M., C.N., H.N., A.-M.S., M.A.S., K.R.S., S.W., R.L., G.D.P.), and the Critical Care Unit, University Hospital Coventry and Warwickshire NHS Trust (M.A.S.), Coventry, Devon Air Ambulance (N.L., B.T.) and South Western Ambulance Service NHS Foundation Trust (R.O., S.W.), Exeter, East Midlands Ambulance Service NHS Trust, Nottingham (R.E.S.S., G.L.S., G.A.W.), East of England Ambulance Service NHS Trust, Cambridge (S.B., T.F.), Kingston University (T.Q.) and London Ambulance Service NHS Trust (R.T.F., J.K., J.F., A.M.-S.), London, North East Ambulance Service NHS Foundation Trust, Newcastle upon Tyne (K.C., E.B., M.L.), North West Ambulance Service NHS Trust, Bolton (S.B., A. Wright, M.W.), South Central Ambulance Service NHS Foundation Trust, Bicester (C.D.D., M.B., A.C., V.D.), South East Coast Ambulance Service NHS Foundation Trust, Crawley (G.B., J.W.), Welsh Ambulance Services University NH...) K Katherine M. Berg L Laurie J. Morrison D Dianne L. Atkins A Allan R. de Caen A Antonio Rodriguez-Nunez F Florian Hoffman E Elliott Acworth A Ashley Bach A Akash Bang N Niklas Breindahl M Michael Adam Carlisle G Genie Castellino K Kaustabh Chaudhuri J Jessie Cunningham G Gurpreet S. Dhillon L Lars Eriksson (Department of Chemistry, Arrhenius Laboratory) M Maria Frazier S Saptharishi L. Ganesan L Lara Goldstein S Seth Gray P Prakriti Gupta M Martha Keinzle M Mirjam Kool J Javier J. Lasa S Suzanne Laughlin J Jaime Lawton D Daniel Loeb (Cincinnati Children's Hospital, Cincinnati, Ohio, United States) W Will McDevitt M Michael Alice Moga A Amanda O’Halloran D Debra Pirrello S Sara-Pier Piscopo L Leandra Rech C Catherine Ross A A. Sahai R Raghavendra Vanaki G George Sam Wang M Mike Wells A Aidan Wilkinson

Abstract

The International Liaison Committee on Resuscitation conducts continuous review of new peer-reviewed published cardiopulmonary resuscitation science and publishes annual summaries. More comprehensive reviews are published every 5 years. The Pediatric Life Support Task Force chapter of the 2025 International Liaison Committee on Resuscitation Consensus on Science With Treatment Recommendations addresses all published resuscitation evidence reviewed by International Liaison Committee on Resuscitation Pediatric Life Support Task Force members in the past year, as well as brief summaries of topics reviewed since 2020, to provide a more comprehensive update. In total, 39 questions related to pre-arrest, intra-arrest, and postarrest resuscitation phases of pediatric cardiac arrest are included, including systematic reviews, scoping reviews, and evidence updates. Members of the task force assessed, discussed, and debated the quality of evidence, based on Grading of Recommendations, Assessment, Development, and Evaluation criteria, and their statements include consensus treatment recommendations. Insights into deliberations of the task force are provided in the Justification and Evidence-to-Decision Framework Highlights sections. The task force has also listed priority knowledge gaps for further research.

Article Details

Journal Circulation
Volume / Issue Vol. 152, Issue 16_suppl_1
Published October 21, 2025
ISSN 0009-7322
Publisher Lippincott Williams & Wilkins

Journal Info

Circulation

Lippincott Williams & Wilkins

ISSN: 0009-7322 Health Sciences

Authors (66)

B

Barnaby R. Scholefield

J

Jason Acworth

K

Kee-Chong Ng

L

Lokesh Kumar Tiwari

T

Tia T. Raymond

A

Andrea Christoff

S

Stephan Katzenschlager

R

Raffo Escalante-Kanashiro

A

Arun Bansal

A

Alexis Topjian

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States

M

Monica Kleinman

H

Hiroshi Kurosawa

M

Michelle C. Myburgh

J

Jimena del Castillo

J

Joseph Rossano

J

Jana Djakow

A

Anne-Marie Guerguerian

The Hospital for Sick Children, Toronto, Ontario, Canada

V

Vinay M. Nadkarni

T

Thomaz Bittencourt Couto

S

Stephen M. Schexnayder

G

Gabrielle Nuthall

J

Janice A. Tijssen

G

Gene Yong-Kwang Ong

J

James M. Gray

J

Jesus López-Herce

E

Ester Shambekela Ambunda

J

Jerry P. Nolan

From the Warwick Medical School, Clinical Trials Unit, University of Warwick (K.C., C.J., J.P.N., J.B.L., J.M.M., F.M., C.N., H.N., A.-M.S., M.A.S., K.R.S., S.W., R.L., G.D.P.), and the Critical Care Unit, University Hospital Coventry and Warwickshire NHS Trust (M.A.S.), Coventry, Devon Air Ambulance (N.L., B.T.) and South Western Ambulance Service NHS Foundation Trust (R.O., S.W.), Exeter, East Midlands Ambulance Service NHS Trust, Nottingham (R.E.S.S., G.L.S., G.A.W.), East of England Ambulance Service NHS Trust, Cambridge (S.B., T.F.), Kingston University (T.Q.) and London Ambulance Service NHS Trust (R.T.F., J.K., J.F., A.M.-S.), London, North East Ambulance Service NHS Foundation Trust, Newcastle upon Tyne (K.C., E.B., M.L.), North West Ambulance Service NHS Trust, Bolton (S.B., A. Wright, M.W.), South Central Ambulance Service NHS Foundation Trust, Bicester (C.D.D., M.B., A.C., V.D.), South East Coast Ambulance Service NHS Foundation Trust, Crawley (G.B., J.W.), Welsh Ambulance Services University NH...

K

Katherine M. Berg

L

Laurie J. Morrison

D

Dianne L. Atkins

A

Allan R. de Caen

A

Antonio Rodriguez-Nunez

F

Florian Hoffman

E

Elliott Acworth

A

Ashley Bach

A

Akash Bang

N

Niklas Breindahl

M

Michael Adam Carlisle

G

Genie Castellino

K

Kaustabh Chaudhuri

J

Jessie Cunningham

G

Gurpreet S. Dhillon

L

Lars Eriksson

Department of Chemistry, Arrhenius Laboratory

M

Maria Frazier

S

Saptharishi L. Ganesan

L

Lara Goldstein

S

Seth Gray

P

Prakriti Gupta

M

Martha Keinzle

M

Mirjam Kool

J

Javier J. Lasa

S

Suzanne Laughlin

J

Jaime Lawton

D

Daniel Loeb

Cincinnati Children's Hospital, Cincinnati, Ohio, United States

W

Will McDevitt

M

Michael Alice Moga

A

Amanda O’Halloran

D

Debra Pirrello

S

Sara-Pier Piscopo

L

Leandra Rech

C

Catherine Ross

A

A. Sahai

R

Raghavendra Vanaki

G

George Sam Wang

M

Mike Wells

A

Aidan Wilkinson