Pathogenicity, virological features, and immune evasion of SARS-CoV-2 JN.1-derived variants including JN.1.7, KP.2, KP.3, and KP.3.1.1

J Jialu Shi X Xiaoyu Zhao X Xiaohui Jin J Jiayan Li Y Yuanchen Liu H Huan Liu Y Ye-Fan Hu Z Zhe Chen (Gladstone Institutes, San Francisco, CA, USA.) Y Yuxin Xiao (Frontiers Science Center for Flexible Electronics, Xi’an Institute of Flexible Electronics & Xi’an Institute of Biomedical Materials and Engineering, Northwestern Polytechnical University, 127 West Youyi Road, Xi’an 710072, China) L Lei Wang Y Yajie Wang (School of Engineering, Westlake University, Hangzhou, China.) Y Yixin He (School of Chemistry and Chemical Engineering, State Key Laboratory of Synergistic Chem-Bio Synthesis, Shanghai Key Laboratory of Electrical Insulation and Thermal Aging) Y Yue Chai B Bingjie Hu (Laboratory of Mammalian Molecular Embryology, Department of Animal Science and Technology, College of Animal Sciences, Zhejiang University) H Huiping Shuai Y Yang Wang X Xiangnan Li (Department of Thoracic Surgery, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China) S Shujun Jiang Y Yanliang Zhang X Xiaojuan Zhang (Zhongshan Institute for Drug Discovery) W Wan-Mui Chan L Lin-Lei Chen J Jian-Piao Cai (Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong) B Baokun Sui H Honglei Zhang D Dong Yang L Longchao Zhu S Shuofeng Yuan J Jie Zhou J Jian-Dong Huang K Kwok-Yung Yuen (Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong) K Kelvin Kai-Wang To (Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong) J Jasper Fuk-Woo Chan (Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong) B Bao-Zhong Zhang Q Qiao Wang M Maozhou He (School of Life Sciences, Westlake University) L Lei Sun P Pengfei Wang (Key Laboratory of Photochemical Conversion and Optoelectronic Materials) H Hin Chu (Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong)

Article Details

Volume / Issue Vol. 16, Issue 1
Published December 11, 2025
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (39)

J

Jialu Shi

X

Xiaoyu Zhao

X

Xiaohui Jin

J

Jiayan Li

Y

Yuanchen Liu

H

Huan Liu

Y

Ye-Fan Hu

Z

Zhe Chen

Gladstone Institutes, San Francisco, CA, USA.

Y

Yuxin Xiao

Frontiers Science Center for Flexible Electronics, Xi’an Institute of Flexible Electronics & Xi’an Institute of Biomedical Materials and Engineering, Northwestern Polytechnical University, 127 West Youyi Road, Xi’an 710072, China

L

Lei Wang

Y

Yajie Wang

School of Engineering, Westlake University, Hangzhou, China.

Y

Yixin He

School of Chemistry and Chemical Engineering, State Key Laboratory of Synergistic Chem-Bio Synthesis, Shanghai Key Laboratory of Electrical Insulation and Thermal Aging

Y

Yue Chai

B

Bingjie Hu

Laboratory of Mammalian Molecular Embryology, Department of Animal Science and Technology, College of Animal Sciences, Zhejiang University

H

Huiping Shuai

Y

Yang Wang

X

Xiangnan Li

Department of Thoracic Surgery, First Affiliated Hospital of Zhengzhou University, Zhengzhou, China

S

Shujun Jiang

Y

Yanliang Zhang

X

Xiaojuan Zhang

Zhongshan Institute for Drug Discovery

W

Wan-Mui Chan

L

Lin-Lei Chen

J

Jian-Piao Cai

Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong

B

Baokun Sui

H

Honglei Zhang

D

Dong Yang

L

Longchao Zhu

S

Shuofeng Yuan

J

Jie Zhou

J

Jian-Dong Huang

K

Kwok-Yung Yuen

Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong

K

Kelvin Kai-Wang To

Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong

J

Jasper Fuk-Woo Chan

Department of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong

B

Bao-Zhong Zhang

Q

Qiao Wang

M

Maozhou He

School of Life Sciences, Westlake University

L

Lei Sun

P

Pengfei Wang

Key Laboratory of Photochemical Conversion and Optoelectronic Materials

H

Hin Chu

Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong