Oxysterol undersulfation promotes osteoarthritis by fueling chondrocyte lipid accumulation

H Huanbo Wang B Bowei Ni Y Yu Qian G Guangyu Ding T Ting He (Division of Thyroid Surgery, Department of General Surgery and Laboratory of Thyroid and Parathyroid Disease, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University) X Xinyu Zhang H Hailun Xu X Xue Hao Y Yaqian Hu D Di Wang Q Qiang Jie Y Ying Li T Tianyang Jie Z Zhong Alan Li Z Zhuojing Luo H Houfeng Zheng L Liu Yang C Chao Zheng (New Cornerstone Science Laboratory, State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, China)

Article Details

Volume / Issue Vol. 17, Issue 1
Published May 19, 2026
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (18)

H

Huanbo Wang

B

Bowei Ni

Y

Yu Qian

G

Guangyu Ding

T

Ting He

Division of Thyroid Surgery, Department of General Surgery and Laboratory of Thyroid and Parathyroid Disease, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University

X

Xinyu Zhang

H

Hailun Xu

X

Xue Hao

Y

Yaqian Hu

D

Di Wang

Q

Qiang Jie

Y

Ying Li

T

Tianyang Jie

Z

Zhong Alan Li

Z

Zhuojing Luo

H

Houfeng Zheng

L

Liu Yang

C

Chao Zheng

New Cornerstone Science Laboratory, State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 345 Lingling Lu, Shanghai 200032, China