Journal of the American Chemical Society

Oxoisoaporphine Alkaloid Iridium(III) Derivative: An Immunogenic Cell Death Inducer That Engages the Autophagy-Dependent Regulator Cathepsin D

Y Yuan Lu F Feng-Yang Wang (Guangxi Colleges and Universities Key Laboratory of Pharmaceutical Biotechnology and Translational Medicine, School of Laboratory Medicine and Biotechnology) M Matthew S. Levine (Department of Chemistry) H Hai-Rong Shi (Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China), Guangxi Key Laboratory of Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences) Y Yuan Wang X Xiaolin Xiong (State Key Laboratory of Anti-Infective Drug Discovery and Development, Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, and School of Pharmaceutical Sciences) L Liang-Mei Yang (Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China), Guangxi Key Laboratory of Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences) Y Ya-Qian Shi (Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China), Guangxi Key Laboratory of Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences) T Taotao Zou (State Key Laboratory of Anti-Infective Drug Discovery and Development, Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, and School of Pharmaceutical Sciences) J Jonathan L. Sessler H Hong Liang (Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China), Guangxi Key Laboratory of Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences) K Ke-Bin Huang (Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China), Guangxi Key Laboratory of Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences)
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Article Details

Volume / Issue Vol. 147, Issue 18
Published May 07, 2025
Pages 15216-15228
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society
ISSN: 0002-7863 Physical Sciences

Authors (12)

Y

Yuan Lu

F

Feng-Yang Wang

Guangxi Colleges and Universities Key Laboratory of Pharmaceutical Biotechnology and Translational Medicine, School of Laboratory Medicine and Biotechnology

M

Matthew S. Levine

Department of Chemistry

H

Hai-Rong Shi

Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China), Guangxi Key Laboratory of Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences

Y

Yuan Wang

X

Xiaolin Xiong

State Key Laboratory of Anti-Infective Drug Discovery and Development, Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, and School of Pharmaceutical Sciences

L

Liang-Mei Yang

Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China), Guangxi Key Laboratory of Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences

Y

Ya-Qian Shi

Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China), Guangxi Key Laboratory of Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences

T

Taotao Zou

State Key Laboratory of Anti-Infective Drug Discovery and Development, Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, and School of Pharmaceutical Sciences

J

Jonathan L. Sessler

H

Hong Liang

Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China), Guangxi Key Laboratory of Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences

K

Ke-Bin Huang

Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China), Guangxi Key Laboratory of Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences

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