Oncogenic Ras drives EED degradation and PRC2 dysfunction to promote aggressive squamous cell carcinoma

M Meng-Yen Li A Aubrey Houser (Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, USA.) P Pradeep Cheema X Xiang Yu Zheng P Paula Restrepo P Pooja Flora Y Yudong Zhou G Gil Segal-Dalal E Eldad Silberstein X Xiaotao Zhang (Tianjin Key Laboratory of Molecular Optoelectronic Sciences, Department of Chemistry, School of Science, Tianjin University and Collaborative Innovation Center of Chemical Science and Engineering, Tianjin 300072, China) M Markus Schober D Deyou Zheng I Idan Cohen A Andrew L. Ji (Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, USA.) E Elena Ezhkova

Article Details

Volume / Issue Vol. 1, Issue 1
Published July 13, 2026
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (15)

M

Meng-Yen Li

A

Aubrey Houser

Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, USA.

P

Pradeep Cheema

X

Xiang Yu Zheng

P

Paula Restrepo

P

Pooja Flora

Y

Yudong Zhou

G

Gil Segal-Dalal

E

Eldad Silberstein

X

Xiaotao Zhang

Tianjin Key Laboratory of Molecular Optoelectronic Sciences, Department of Chemistry, School of Science, Tianjin University and Collaborative Innovation Center of Chemical Science and Engineering, Tianjin 300072, China

M

Markus Schober

D

Deyou Zheng

I

Idan Cohen

A

Andrew L. Ji

Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, USA.

E

Elena Ezhkova