Of the article: Microbiological assessment of a herbal mouth rinse for treating chronic generalized periodontitis

S Svetlana Razumova S Sergey Panov A Anna Marakhova I Irina Koroleva E Ekaterina Mikhailova A Anzhela Brago H Haydar Barakat

Abstract

Abstract Periodontal diseases remain highly prevalent across age groups, often aggravated by poor oral hygiene, occlusal anomalies, and defective restorations. This study evaluated the effectiveness of Art-Dentale Expert mouthwash against major periodontopathogens in patients with mild chronic generalized periodontitis (CGP) using PCR diagnostics. Thirty-nine patients with CGP were randomized into a main group (Art-Dentale Expert) and a control group (Chlorhexidine). Gingival pocket samples were collected before treatment and at 7 days, 1 month, and 6 months. Four periodontopathogens (P. gingivalis, T. forsythia, T. denticola, and P. intermedia) were analyzed. The results obtained were processed statistically. Both rinses significantly reduced P. gingivalis and T. forsythia at 7 days, with Chlorhexidine showing a sharper initial decline in P. gingivalis. At 6 months, P. intermedia was completely absent in the Art-Dentale Expert group ( p  = 0.0209), whereas it persisted in 10% of controls. Art-Dentale Expert demonstrated sustained efficacy, particularly against T. denticola and P. intermedia. These findings support its role as an effective adjunct in periodontal therapy.

Article Details

Volume / Issue Vol. 15, Issue 1
Published October 31, 2025
ISSN 2045-2322
Publisher Nature Portfolio

Journal Info

Scientific Reports

Nature Portfolio

ISSN: 2045-2322 Open Access Life Sciences

Authors (7)

S

Svetlana Razumova

S

Sergey Panov

A

Anna Marakhova

I

Irina Koroleva

E

Ekaterina Mikhailova

A

Anzhela Brago

H

Haydar Barakat