NR2F6 deletion revives CAR-T cell function and induces antigen-agnostic immune memory in solid tumors

Dominik Humer; Victoria Klepsch; Dietmar Rieder; Isabel Hölzl; Daniel Schreiber; Viktor Lang; Jiří Koutník; Sebastian Peer; Tajana Sajinovic; Viana Wille; Anna Fürst; Dragana Savic; Gabriel Diem; Wilfried Posch; Ira-Ida Skvortsova; Anne Krogsdam; Sieghart Sopper; Sebastian Kobold; Zlatko Trajanoski; Kerstin Siegmund; Nikolaus Thuille; Thomas Gruber; Dominik Wolf; Gottfried Baier

doi:10.1038/s41467-026-69796-0

NR2F6 deletion revives CAR-T cell function and induces antigen-agnostic immune memory in solid tumors

D Dominik Humer V Victoria Klepsch D Dietmar Rieder I Isabel Hölzl D Daniel Schreiber V Viktor Lang J Jiří Koutník S Sebastian Peer T Tajana Sajinovic V Viana Wille A Anna Fürst D Dragana Savic G Gabriel Diem W Wilfried Posch I Ira-Ida Skvortsova A Anne Krogsdam S Sieghart Sopper S Sebastian Kobold Z Zlatko Trajanoski K Kerstin Siegmund N Nikolaus Thuille T Thomas Gruber D Dominik Wolf G Gottfried Baier

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Article Details

Journal Nature Communications

Volume / Issue Vol. 17, Issue 1

Published February 27, 2026

DOI 10.1038/s41467-026-69796-0

ISSN 2041-1723

Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (24)

D

Dominik Humer

V

Victoria Klepsch

D

Dietmar Rieder

I

Isabel Hölzl

D

Daniel Schreiber

V

Viktor Lang

J

Jiří Koutník

S

Sebastian Peer

T

Tajana Sajinovic

V

Viana Wille

A

Anna Fürst

D

Dragana Savic

G

Gabriel Diem

W

Wilfried Posch

I

Ira-Ida Skvortsova

A

Anne Krogsdam

S

Sieghart Sopper

S

Sebastian Kobold

Z

Zlatko Trajanoski

K

Kerstin Siegmund

N

Nikolaus Thuille

T

Thomas Gruber

D

Dominik Wolf

G

Gottfried Baier

NR2F6 deletion revives CAR-T cell function and induces antigen-agnostic immune memory in solid tumors

Article Details

Journal Info

Authors (24)

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