Network toxicology, transcriptomics, and cytotoxic validation reveal TDCPP-induced pterygium mechanisms

Ji Yang; Jiajie Li; Boyu Liang; Nishan Zhao; Peng Zhang; ChengYan Fang; Tao Xie; Ping Xiang; Hai Liu

doi:10.1038/s41598-025-26338-w

Network toxicology, transcriptomics, and cytotoxic validation reveal TDCPP-induced pterygium mechanisms

J Ji Yang (New Cornerstone Science Laboratory, State Key Laboratory for Physical Chemistry of Solid Surfaces, Collaborative Innovation Center of Chemistry for Energy Materials, and National & Local Joint Engineering Research Center of Preparation Technology of Nanomaterials, College of Chemistry and Chemical Engineering) J Jiajie Li B Boyu Liang N Nishan Zhao P Peng Zhang C ChengYan Fang T Tao Xie (Zhejiang University , , ,) P Ping Xiang H Hai Liu (Key Laboratory of Leather Chemistry and Engineering of Ministry of Education, National Engineering Laboratory for Clean Technology of Leather Manufacture)

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Article Details

Journal Scientific Reports

Volume / Issue Vol. 15, Issue 1

Published November 07, 2025

DOI 10.1038/s41598-025-26338-w

ISSN 2045-2322

Publisher Nature Portfolio

Journal Info

Scientific Reports

Nature Portfolio

ISSN: 2045-2322 Open Access Life Sciences

Authors (9)

J

Ji Yang

New Cornerstone Science Laboratory, State Key Laboratory for Physical Chemistry of Solid Surfaces, Collaborative Innovation Center of Chemistry for Energy Materials, and National & Local Joint Engineering Research Center of Preparation Technology of Nanomaterials, College of Chemistry and Chemical Engineering

J

Jiajie Li

B

Boyu Liang

N

Nishan Zhao

P

Peng Zhang

C

ChengYan Fang

T

Tao Xie

Zhejiang University , , ,

P

Ping Xiang

H

Hai Liu

Key Laboratory of Leather Chemistry and Engineering of Ministry of Education, National Engineering Laboratory for Clean Technology of Leather Manufacture

Network toxicology, transcriptomics, and cytotoxic validation reveal TDCPP-induced pterygium mechanisms

Article Details

Journal Info

Authors (9)

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