Native CFTR codon bias controls translation rate to balance off-pathway aggregation and channel function by conformational imprinting

J Jae Seok Yoon H Hongyu Li Y Yonjung Kim H Hideki Shishido D David N. Sheppard (School of Physiology, Pharmacology and Neuroscience, University of Bristol) M Min Goo Lee (Brain Korea 21 project for Medical Science, Yonsei University College of Medicine) W William R. Skach

Article Details

Volume / Issue Vol. 16, Issue 1
Published December 12, 2025
ISSN 2045-2322
Publisher Nature Portfolio

Journal Info

Scientific Reports

Nature Portfolio

ISSN: 2045-2322 Open Access Life Sciences

Authors (7)

J

Jae Seok Yoon

H

Hongyu Li

Y

Yonjung Kim

H

Hideki Shishido

D

David N. Sheppard

School of Physiology, Pharmacology and Neuroscience, University of Bristol

M

Min Goo Lee

Brain Korea 21 project for Medical Science, Yonsei University College of Medicine

W

William R. Skach