MVT-Net: A novel cervical tumour segmentation using multi-view feature transfer learning

Y Yao Yao Y Yunzhi Chen A An Yang Y Ye Ye L Lichun Wei S Shuiping Gou H Hua Yang (State Key Laboratory of Natural Medicines, School of Pharmacy, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, China)

Abstract

Cervical cancer is one of the most aggressive malignant tumours of the reproductive system, posing a significant global threat to women’s health. Accurately segmenting cervical tumours in MR images remains a challenging task due to the complex characteristics of tumours and the limitations of traditional methods. To address these challenges, this study proposes a novel cervical tumour segmentation model based on multi-view feature transfer learning, named MVT-Net. The model integrates a 2D global axial plane encoder-decoder network and a 3D multi-scale segmentation network as source and target domains, respectively. A transfer learning strategy is employed to extract diverse tumour-related information from multiple perspectives. In addition, a multi-scale residual blocks and a multi-scale residual attention blocks are embedded in the 3D network to effectively capture feature correlations across channels and spatial positions. Experiments on a cervical MR dataset of 160 images show that our proposed MVT-Net outperforms state-of-the-art methods, achieving a DICE score of 75.9±7.43%, an ASD of 2.69±0.58 mm and superior performance in tumour localisation, shape delineation and edge segmentation. Ablation studies further validate the effectiveness of the proposed multi-view feature transfer strategy. These results demonstrate that our proposed MVT-Net represents a significant advance in cervical tumour segmentation, offering improved accuracy and reliability in clinical applications.

Article Details

Journal PLoS ONE
Volume / Issue Vol. 20, Issue 6
Published June 24, 2025
Pages e0325424
ISSN 1932-6203
Publisher Public Library of Science

Journal Info

PLoS ONE

Public Library of Science

ISSN: 1932-6203 Open Access Health Sciences

Authors (7)

Y

Yao Yao

Y

Yunzhi Chen

A

An Yang

Y

Ye Ye

L

Lichun Wei

S

Shuiping Gou

H

Hua Yang

State Key Laboratory of Natural Medicines, School of Pharmacy, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, China