Multi-perspective dynamic consistency learning for semi-supervised medical image segmentation

Y Yongfa Zhu (Department of Chemistry) X Xue Wang T Taihui Liu Y Yongkang Fu

Abstract

Abstract Semi-supervised learning (SSL) is an effective method for medical image segmentation as it alleviates the dependence on clinical pixel-level annotations. Among the SSL methods, pseudo-labels and consistency regularization play a key role as the dominant paradigm. However, current consistency regularization methods based on shared encoder structures are prone to trap the model in cognitive bias, which impairs the segmentation performance. Furthermore, traditional fixed-threshold-based pseudo-label selection methods lack the utilization of low-confidence pixels, making the model’s initial segmentation capability insufficient, especially for confusing regions. To this end, we propose a multi-perspective dynamic consistency (MPDC) framework to mitigate model cognitive bias and to fully utilize the low-confidence pixels. Specially, we propose a novel multi-perspective collaborative learning strategy that encourages the sub-branch networks to learn discriminative features from multiple perspectives, thus avoiding the problem of model cognitive bias and enhancing boundary perception. In addition, we further employ a dynamic decoupling consistency scheme to fully utilize low-confidence pixels. By dynamically adjusting the threshold, more pseudo-labels are involved in the early stages of training. Extensive experiments on several challenging medical image segmentation datasets show that our method achieves state-of-the-art performance, especially on boundaries, with significant improvements.

Article Details

Volume / Issue Vol. 15, Issue 1
Published May 25, 2025
ISSN 2045-2322
Publisher Nature Portfolio

Journal Info

Scientific Reports

Nature Portfolio

ISSN: 2045-2322 Open Access Life Sciences

Authors (4)

Y

Yongfa Zhu

Department of Chemistry

X

Xue Wang

T

Taihui Liu

Y

Yongkang Fu