Multi-modal skin atlas identifies a multicellular immune-stromal community associated with disrupted cornification and specific T cell expansion in atopic dermatitis

Evgenij Fiskin; Gökcen Eraslan; Maria B. Alora-Palli; Tanvi Jain; Juan Manuel Leyva-Castillo; Sean Kim; Heather Choe; Caleb A. Lareau; Helena Lau; Emily P. Finan; Isabella Teixeira-Soldano; Brenna LaBere; Anne Chu; Brian Woods; Janet Chou; Michal Slyper; Julia Waldman; Sabina Islam; Lynda Schneider; Wanda Phipatanakul; Craig Platt; Orit Rozenblatt-Rosen; Toni M. Delorey; Orr Ashenberg; Jacques Deguine; Gideon P. Smith; Raif S. Geha; Aviv Regev; Ramnik J. Xavier

doi:10.1038/s41467-026-69587-7

Multi-modal skin atlas identifies a multicellular immune-stromal community associated with disrupted cornification and specific T cell expansion in atopic dermatitis

E Evgenij Fiskin G Gökcen Eraslan M Maria B. Alora-Palli T Tanvi Jain J Juan Manuel Leyva-Castillo S Sean Kim H Heather Choe C Caleb A. Lareau H Helena Lau E Emily P. Finan I Isabella Teixeira-Soldano B Brenna LaBere A Anne Chu B Brian Woods J Janet Chou M Michal Slyper J Julia Waldman S Sabina Islam L Lynda Schneider W Wanda Phipatanakul C Craig Platt O Orit Rozenblatt-Rosen T Toni M. Delorey O Orr Ashenberg J Jacques Deguine G Gideon P. Smith R Raif S. Geha A Aviv Regev R Ramnik J. Xavier

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Article Details

Journal Nature Communications

Volume / Issue Vol. 17, Issue 1

Published February 25, 2026

DOI 10.1038/s41467-026-69587-7

ISSN 2041-1723

Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (29)

E

Evgenij Fiskin

G

Gökcen Eraslan

M

Maria B. Alora-Palli

T

Tanvi Jain

J

Juan Manuel Leyva-Castillo

S

Sean Kim

H

Heather Choe

C

Caleb A. Lareau

H

Helena Lau

E

Emily P. Finan

I

Isabella Teixeira-Soldano

B

Brenna LaBere

A

Anne Chu

B

Brian Woods

J

Janet Chou

M

Michal Slyper

J

Julia Waldman

S

Sabina Islam

L

Lynda Schneider

W

Wanda Phipatanakul

C

Craig Platt

O

Orit Rozenblatt-Rosen

T

Toni M. Delorey

O

Orr Ashenberg

J

Jacques Deguine

G

Gideon P. Smith

R

Raif S. Geha

A

Aviv Regev

R

Ramnik J. Xavier

Multi-modal skin atlas identifies a multicellular immune-stromal community associated with disrupted cornification and specific T cell expansion in atopic dermatitis

Article Details

Journal Info

Authors (29)

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