Mitochondrial damage in muscle specific PolG mutant mice activates the integrated stress response and disrupts the mitochondrial folate cycle

S Simon T. Bond E Emily J. King S Shannen M. Walker C Christine Yang Y Yingying Liu (Institute of Intelligent Machines, Hefei Institutes of Physical Science) K Kevin H. Liu A Aowen Zhuang A Aaron W. Jurrjens H Haoyun A. Fang L Luke E. Formosa A Artika P. Nath S Sergio Ruiz Carmona M Michael Inouye T Thy Duong (Pediatric Surgical Research Laboratories, Massachusetts General Hospital) K Kevin Huynh P Peter J. Meikle S Simon Crawford G Georg Ramm S Sheik Nadeem Elahee Doomun D David P. de Souza D Danielle L. Rudler A Anna C. Calkin A Aleksandra Filipovska D David W. Greening D Darren C. Henstridge B Brian G. Drew

Article Details

Volume / Issue Vol. 16, Issue 1
Published March 08, 2025
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (26)

S

Simon T. Bond

E

Emily J. King

S

Shannen M. Walker

C

Christine Yang

Y

Yingying Liu

Institute of Intelligent Machines, Hefei Institutes of Physical Science

K

Kevin H. Liu

A

Aowen Zhuang

A

Aaron W. Jurrjens

H

Haoyun A. Fang

L

Luke E. Formosa

A

Artika P. Nath

S

Sergio Ruiz Carmona

M

Michael Inouye

T

Thy Duong

Pediatric Surgical Research Laboratories, Massachusetts General Hospital

K

Kevin Huynh

P

Peter J. Meikle

S

Simon Crawford

G

Georg Ramm

S

Sheik Nadeem Elahee Doomun

D

David P. de Souza

D

Danielle L. Rudler

A

Anna C. Calkin

A

Aleksandra Filipovska

D

David W. Greening

D

Darren C. Henstridge

B

Brian G. Drew