Mipep deficiency in adipocytes impairs mitochondrial protein maturation and leads to systemic inflammation and metabolic dysfunctions

Yuka Nozaki; Masaki Kobayashi; Tomoyoshi Fukuoh; Mamiko Ishimatsu; Takumi Narita; Kanari Taki; Yuto Hirao; Shota Ayabe; Miku Yokoyama; Yuina Otani; Yuhei Mizunoe; Mami Matsumoto; Nobuhiko Ohno; Tomonori Kaifu; Shogo Okazaki; Ryo Goitsuka; Yoshimi Nakagawa; Hitoshi Shimano; Yoichiro Iwakura; Yoshikazu Higami

doi:10.1038/s41598-025-97307-6

Mipep deficiency in adipocytes impairs mitochondrial protein maturation and leads to systemic inflammation and metabolic dysfunctions

Y Yuka Nozaki M Masaki Kobayashi T Tomoyoshi Fukuoh M Mamiko Ishimatsu T Takumi Narita K Kanari Taki Y Yuto Hirao S Shota Ayabe M Miku Yokoyama Y Yuina Otani Y Yuhei Mizunoe M Mami Matsumoto N Nobuhiko Ohno (Division of Histology and Cell Biology, Department of Anatomy, Jichi Medical University) T Tomonori Kaifu S Shogo Okazaki R Ryo Goitsuka Y Yoshimi Nakagawa H Hitoshi Shimano Y Yoichiro Iwakura Y Yoshikazu Higami

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Article Details

Journal Scientific Reports

Volume / Issue Vol. 15, Issue 1

Published April 14, 2025

DOI 10.1038/s41598-025-97307-6

ISSN 2045-2322

Publisher Nature Portfolio

Journal Info

Scientific Reports

Nature Portfolio

ISSN: 2045-2322 Open Access Life Sciences

Authors (20)

Y

Yuka Nozaki

M

Masaki Kobayashi

T

Tomoyoshi Fukuoh

M

Mamiko Ishimatsu

T

Takumi Narita

K

Kanari Taki

Y

Yuto Hirao

S

Shota Ayabe

M

Miku Yokoyama

Y

Yuina Otani

Y

Yuhei Mizunoe

M

Mami Matsumoto

N

Nobuhiko Ohno

Division of Histology and Cell Biology, Department of Anatomy, Jichi Medical University

T

Tomonori Kaifu

S

Shogo Okazaki

R

Ryo Goitsuka

Y

Yoshimi Nakagawa

H

Hitoshi Shimano

Y

Yoichiro Iwakura

Y

Yoshikazu Higami

Mipep deficiency in adipocytes impairs mitochondrial protein maturation and leads to systemic inflammation and metabolic dysfunctions

Article Details

Journal Info

Authors (20)

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