Marine Natural Product Chagosendine C Induces Cuproptosis in Colorectal Cancer Cells by Targeting FDX1

X Xiaoyu Tao (State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Shanghai Frontiers Science Center of TCM Chemical Biology, Institute of Interdisciplinary Integrative Medicine Research) H Hongru Wang (State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Shanghai Frontiers Science Center of TCM Chemical Biology, Institute of Interdisciplinary Integrative Medicine Research) Q Qun Wang (State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Shanghai Frontiers Science Center of TCM Chemical Biology, Institute of Interdisciplinary Integrative Medicine Research) C Chengji Wang (Shanghai Laboratory Animal Research Center) C Chang-Wei Shao (Shandong Laboratory of Yantai Drug Discovery) Y Yang Jin (School of Materials Science and Engineering) D Dianping Yu (State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Shanghai Frontiers Science Center of TCM Chemical Biology, Institute of Interdisciplinary Integrative Medicine Research) H Hongmei Hu (State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Shanghai Frontiers Science Center of TCM Chemical Biology, Institute of Interdisciplinary Integrative Medicine Research) Q Qing Zhang M Mengting Xu (State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Shanghai Frontiers Science Center of TCM Chemical Biology, Institute of Interdisciplinary Integrative Medicine Research) X Xiangxin Geng (State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Shanghai Frontiers Science Center of TCM Chemical Biology, Institute of Interdisciplinary Integrative Medicine Research) H Hanchi Xu (State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Shanghai Frontiers Science Center of TCM Chemical Biology, Institute of Interdisciplinary Integrative Medicine Research) L LinYang Li (College of Chemical & Environment Science) R Ruling Shen (Shanghai Laboratory Animal Research Center) Y Yue-Wei Guo (Shandong Laboratory of Yantai Drug Discovery) X Xu-Wen Li (State Key Laboratory of Chemical Biology) S Sanhong Liu (State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Shanghai Frontiers Science Center of TCM Chemical Biology, Institute of Interdisciplinary Integrative Medicine Research) W Weidong Zhang (Department of Materials Science and Engineering)

Article Details

Volume / Issue Vol. 147, Issue 41
Published October 15, 2025
Pages 37089-37103
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (18)

X

Xiaoyu Tao

State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Shanghai Frontiers Science Center of TCM Chemical Biology, Institute of Interdisciplinary Integrative Medicine Research

H

Hongru Wang

State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Shanghai Frontiers Science Center of TCM Chemical Biology, Institute of Interdisciplinary Integrative Medicine Research

Q

Qun Wang

State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Shanghai Frontiers Science Center of TCM Chemical Biology, Institute of Interdisciplinary Integrative Medicine Research

C

Chengji Wang

Shanghai Laboratory Animal Research Center

C

Chang-Wei Shao

Shandong Laboratory of Yantai Drug Discovery

Y

Yang Jin

School of Materials Science and Engineering

D

Dianping Yu

State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Shanghai Frontiers Science Center of TCM Chemical Biology, Institute of Interdisciplinary Integrative Medicine Research

H

Hongmei Hu

State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Shanghai Frontiers Science Center of TCM Chemical Biology, Institute of Interdisciplinary Integrative Medicine Research

Q

Qing Zhang

M

Mengting Xu

State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Shanghai Frontiers Science Center of TCM Chemical Biology, Institute of Interdisciplinary Integrative Medicine Research

X

Xiangxin Geng

State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Shanghai Frontiers Science Center of TCM Chemical Biology, Institute of Interdisciplinary Integrative Medicine Research

H

Hanchi Xu

State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Shanghai Frontiers Science Center of TCM Chemical Biology, Institute of Interdisciplinary Integrative Medicine Research

L

LinYang Li

College of Chemical & Environment Science

R

Ruling Shen

Shanghai Laboratory Animal Research Center

Y

Yue-Wei Guo

Shandong Laboratory of Yantai Drug Discovery

X

Xu-Wen Li

State Key Laboratory of Chemical Biology

S

Sanhong Liu

State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine, Shanghai Frontiers Science Center of TCM Chemical Biology, Institute of Interdisciplinary Integrative Medicine Research

W

Weidong Zhang

Department of Materials Science and Engineering