Proceedings of the National Academy of Sciences

MALT1 inhibitor MI-2 induces ferroptosis by direct targeting of GPX4

E Eikan Mishima T Thomas J. O’Neill (Research Unit Signaling and Translation, Group Signaling and Immunity, Molecular Targets and Therapeutics Center, Helmholtz Munich) K Kai P. Hoefig (Research Unit Molecular Immune Regulation, Molecular Targets and Therapeutics Center, Helmholtz Munich) D Deng Chen (Institute of Metabolism and Cell Death, Molecular Targets and Therapeutics Center, Helmholtz Munich) G Gesine Behrens (Research Unit Molecular Immune Regulation, Molecular Targets and Therapeutics Center, Helmholtz Munich) B Bernhard Henkelmann (Institute of Metabolism and Cell Death, Molecular Targets and Therapeutics Center, Helmholtz Munich) J Junya Ito (Laboratory of Food Function Analysis, Graduate School of Agricultural Science, Tohoku University) K Kiyotaka Nakagawa (Laboratory of Food Function Analysis, Graduate School of Agricultural Science, Tohoku University) V Vigo Heissmeyer (Research Unit Molecular Immune Regulation, Molecular Targets and Therapeutics Center, Helmholtz Munich) M Marcus Conrad D Daniel Krappmann (Research Unit Signaling and Translation, Group Signaling and Immunity, Molecular Targets and Therapeutics Center, Helmholtz Munich)
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Article Details

Volume / Issue Vol. 122, Issue 20
Published May 20, 2025
ISSN 0027-8424
Publisher National Academy of Sciences

Journal Info

Proceedings of the National Academy of Sciences

National Academy of Sciences
ISSN: 0027-8424 Life Sciences

Authors (11)

E

Eikan Mishima

T

Thomas J. O’Neill

Research Unit Signaling and Translation, Group Signaling and Immunity, Molecular Targets and Therapeutics Center, Helmholtz Munich

K

Kai P. Hoefig

Research Unit Molecular Immune Regulation, Molecular Targets and Therapeutics Center, Helmholtz Munich

D

Deng Chen

Institute of Metabolism and Cell Death, Molecular Targets and Therapeutics Center, Helmholtz Munich

G

Gesine Behrens

Research Unit Molecular Immune Regulation, Molecular Targets and Therapeutics Center, Helmholtz Munich

B

Bernhard Henkelmann

Institute of Metabolism and Cell Death, Molecular Targets and Therapeutics Center, Helmholtz Munich

J

Junya Ito

Laboratory of Food Function Analysis, Graduate School of Agricultural Science, Tohoku University

K

Kiyotaka Nakagawa

Laboratory of Food Function Analysis, Graduate School of Agricultural Science, Tohoku University

V

Vigo Heissmeyer

Research Unit Molecular Immune Regulation, Molecular Targets and Therapeutics Center, Helmholtz Munich

M

Marcus Conrad

D

Daniel Krappmann

Research Unit Signaling and Translation, Group Signaling and Immunity, Molecular Targets and Therapeutics Center, Helmholtz Munich

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