Macrophage ALDH2 drives immunotherapy resistance by silencing CXCL9 through metabolic-epigenetic crosstalk

H Huiying Fang J Jiazheng Sun Q Qian Xiao H He Ren (Department of Oncology, Beijing Shijitan Hospital, Capital Medical University) Y Yuru Chen J Jiazhou Liu D Daqiang Song T Tiantian Chen L Linling Wu P Pin Wang (Ningbo Key Laboratory of Biomedical Imaging Probe Materials and Technology, Laboratory of Advanced Theranostic Materials and Technology) J Jian Yue (Department of Microbial Pathogenesis, Yale School of Medicine) X Xiaoyu Wang Q Qilin Yang (Key Laboratory of Seed Innovation, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences) Y Yuxian Wei H Huimin Du W Weiyan Peng Z Zhu Qiu L Li Zhang J Jingyuan Wan T Tong Liu G Guosheng Ren H Hongzhong Li

Article Details

Volume / Issue Vol. 1, Issue 1
Published May 21, 2026
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (22)

H

Huiying Fang

J

Jiazheng Sun

Q

Qian Xiao

H

He Ren

Department of Oncology, Beijing Shijitan Hospital, Capital Medical University

Y

Yuru Chen

J

Jiazhou Liu

D

Daqiang Song

T

Tiantian Chen

L

Linling Wu

P

Pin Wang

Ningbo Key Laboratory of Biomedical Imaging Probe Materials and Technology, Laboratory of Advanced Theranostic Materials and Technology

J

Jian Yue

Department of Microbial Pathogenesis, Yale School of Medicine

X

Xiaoyu Wang

Q

Qilin Yang

Key Laboratory of Seed Innovation, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences

Y

Yuxian Wei

H

Huimin Du

W

Weiyan Peng

Z

Zhu Qiu

L

Li Zhang

J

Jingyuan Wan

T

Tong Liu

G

Guosheng Ren

H

Hongzhong Li