Loss of O-GlcNAcylation in cardiac myocytes triggers the integrated stress response, contributing to heart failure

Kyriakos N. Papanicolaou; Wenxi Zhang; Aidan J. Dunphy; Justin C. Zhong; Clara Y. Cho; Dan R. Turner; Deepthi Ashok; D. Brian Foster; Brian O’Rourke; Natasha E. Zachara

doi:10.1016/j.jbc.2025.110818

Loss of O-GlcNAcylation in cardiac myocytes triggers the integrated stress response, contributing to heart failure

K Kyriakos N. Papanicolaou W Wenxi Zhang A Aidan J. Dunphy J Justin C. Zhong C Clara Y. Cho D Dan R. Turner D Deepthi Ashok D D. Brian Foster B Brian O’Rourke N Natasha E. Zachara

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Article Details

Journal Journal of Biological Chemistry

Volume / Issue Vol. 301, Issue 12

Published December 01, 2025

Pages 110818

DOI 10.1016/j.jbc.2025.110818

ISSN 0021-9258

Publisher Elsevier BV

Journal Info

Journal of Biological Chemistry

Elsevier BV

ISSN: 0021-9258 Open Access Life Sciences

Authors (10)

K

Kyriakos N. Papanicolaou

W

Wenxi Zhang

A

Aidan J. Dunphy

J

Justin C. Zhong

C

Clara Y. Cho

D

Dan R. Turner

D

Deepthi Ashok

D

D. Brian Foster

B

Brian O’Rourke

N

Natasha E. Zachara

Loss of O-GlcNAcylation in cardiac myocytes triggers the integrated stress response, contributing to heart failure

Article Details

Journal Info

Authors (10)

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