Loss of DNA methyltransferase 3a enhances Caspase-8 transcription and promotes cardiomyocyte pyroptosis during myocardial infarction

N Ning Wang L Liling Gong X Xingmiao Zhao W Wenshuang Zhao N Ning Xu X Ximing Chen (State Key Laboratory of Physical Chemistry of Solid Surfaces, Key Laboratory for Chemical Biology of Fujian Province, The MOE Key Laboratory of Spectro-Chemical Analysis & Instrumentation, Department of Chemical Biology, College of Chemistry and Chemical Engineering) Q Qingwei Zhang M Ming Li Y Yijing Yao H Hang Yu (Beijing National Laboratory for Molecular Science, State Key Laboratory of Rare Earth Materials Chemistry and Applications, College of Chemistry and Molecular Engineering) Q Qingsui Li L Liwei Zhu L Long Qin X Xu Su Z Zhen Zhang W Wei Li W Wanyu Zhang (Department of Chemical and Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, Singapore 117585, Singapore) Y Yadong Xue X Xianzhi Lang P Pengyu Li S Sijia Li S Siyu Chang J Jiamin Li B Benzhi Cai (Department of Pharmacy at the Second Affiliated Hospital, Harbin Medical University)

Article Details

Volume / Issue Vol. 17, Issue 1
Published April 22, 2026
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (24)

N

Ning Wang

L

Liling Gong

X

Xingmiao Zhao

W

Wenshuang Zhao

N

Ning Xu

X

Ximing Chen

State Key Laboratory of Physical Chemistry of Solid Surfaces, Key Laboratory for Chemical Biology of Fujian Province, The MOE Key Laboratory of Spectro-Chemical Analysis & Instrumentation, Department of Chemical Biology, College of Chemistry and Chemical Engineering

Q

Qingwei Zhang

M

Ming Li

Y

Yijing Yao

H

Hang Yu

Beijing National Laboratory for Molecular Science, State Key Laboratory of Rare Earth Materials Chemistry and Applications, College of Chemistry and Molecular Engineering

Q

Qingsui Li

L

Liwei Zhu

L

Long Qin

X

Xu Su

Z

Zhen Zhang

W

Wei Li

W

Wanyu Zhang

Department of Chemical and Biomolecular Engineering, National University of Singapore, 4 Engineering Drive 4, Singapore 117585, Singapore

Y

Yadong Xue

X

Xianzhi Lang

P

Pengyu Li

S

Sijia Li

S

Siyu Chang

J

Jiamin Li

B

Benzhi Cai

Department of Pharmacy at the Second Affiliated Hospital, Harbin Medical University