Liquid-nano-liquid interface–oriented anisotropic encapsulation
Abstract
Emulsion interface engineering has been widely employed for the synthesis of nanomaterials with various morphologies. However, the instability of the liquid–liquid interface and uncertain interfacial interactions impose significant limitations on controllable fabrications. Here, we developed a liquid-nano-liquid interface–oriented anisotropic encapsulation strategy for fabricating asymmetric nanohybrids. Specifically, functional nanoparticles such as magnetic nanoparticles, lanthanide fluorescent nanoparticles, and Au nanorods were anisotropically encapsulated by mesoporous polydopamine (mPDA). In this emulsion system, the wetting behavior of functional nanoparticles at the water/oil interface could be manipulated by the stabilizer of the emulsion (surfactant), leading to the anisotropic assembly of mPDA shell and resulting in various nanostructures, including core–shell, yolk–shell with small opening, ball-in-bowl, and multipetal structures. Due to their structural asymmetry, inherent magnetic properties, and photothermal properties, the ball-in-bowl structured Fe 3 O 4 @SiO 2 &mPDA nanohybrids, serving as proof of concept for nanomotors, demonstrated effective penetration of bacterial biofilm and promotion of infected wound healing. Overall, our approach offers a different perspective for designing morphologically controllable asymmetric structures based on liquid-nano-liquid interface in microemulsion systems that hold great potential for establishing innovative functional nanomaterials.
Article Details
Journal Info
Proceedings of the National Academy of Sciences
National Academy of Sciences
Authors (12)
Yating Zhan
Department of Chemistry, Shanghai Stomatological Hospital & School of Stomatology, State Key Laboratory of Molecular Engineering of Polymers, iChem (Collaborative Innovation Center of Chemistry for Energy Materials), Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials
Xirui Huang
College of Chemistry and Materials, Department of Chemistry, Department of Macromolecular Science, Laboratory of Advanced Materials, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, State Key Laboratory of Molecular Engineering of Polymers, Collaborative Innovation Center of Chemistry for Energy Materials (2011-ChEM)
Minchao Liu
Runfeng Lin
College of Chemistry and Materials, Department of Chemistry, Department of Macromolecular Science, Laboratory of Advanced Materials, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, State Key Laboratory of Molecular Engineering of Polymers, Collaborative Innovation Center of Chemistry for Energy Materials (2011-ChEM)
Hongyue Yu
Department of Chemistry, Shanghai Stomatological Hospital & School of Stomatology, State Key Laboratory of Molecular Engineering of Polymers, iChem (Collaborative Innovation Center of Chemistry for Energy Materials), Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials
Yufang Kou
Department of Chemistry, Shanghai Stomatological Hospital & School of Stomatology, State Key Laboratory of Molecular Engineering of Polymers, iChem (Collaborative Innovation Center of Chemistry for Energy Materials), Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials
Enyun Xing
Department of Chemistry, Shanghai Stomatological Hospital & School of Stomatology, State Key Laboratory of Molecular Engineering of Polymers, iChem (Collaborative Innovation Center of Chemistry for Energy Materials), Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials
Ahmed A. Elzatahry
William A. Brookshire Department of Chemical and Biomolecular Engineering, Cullen College of Engineering
Mohamed F. Mady
Department of Chemistry and Earth Sciences, College of Arts and Sciences
Dongyuan Zhao
Laboratory of Advanced Materials, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, State Key Laboratory of Porous Materials for Separation and Conversion, Fudan University, 220 Handan, Shanghai 200433, P. R. China
Tiancong Zhao
Department of Chemistry, Shanghai Stomatological Hospital & School of Stomatology, State Key Laboratory of Molecular Engineering of Polymers, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials
Xiaomin Li
Department of Chemistry, Shanghai Stomatological Hospital & School of Stomatology, State Key Laboratory of Molecular Engineering of Polymers, iChem (Collaborative Innovation Center of Chemistry for Energy Materials), Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials