Ligand-activated EGFR/MAPK signaling but not PI3K, are key resistance mechanisms to EGFR-therapy in colorectal cancer

X Xueping Qu H Habib Hamidi R Radia M. Johnson E Ethan S. Sokol E Eva Lin (Merck Center for Catalysis at Princeton University) C Cathy Eng (Vanderbilt-Ingram Cancer Center, Nashville) T Tae Won Kim (Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea) J Johanna Bendell S Smruthy Sivakumar B Benjamin Kaplan F Felipe De Sousa E Melo A Andrew Mancini M Matthew Wongchenko Y Yi Shi (School of Materials Science and Engineering, Key Laboratory for Polymeric Composite and Functional Materials of Ministry of Education, Guangdong Functional Biomaterials Engineering Technology Research Center) D David Shames Y Yibing Yan F Fortunato Ciardiello C Carlos Bais

Article Details

Volume / Issue Vol. 16, Issue 1
Published May 09, 2025
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (18)

X

Xueping Qu

H

Habib Hamidi

R

Radia M. Johnson

E

Ethan S. Sokol

E

Eva Lin

Merck Center for Catalysis at Princeton University

C

Cathy Eng

Vanderbilt-Ingram Cancer Center, Nashville

T

Tae Won Kim

Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea

J

Johanna Bendell

S

Smruthy Sivakumar

B

Benjamin Kaplan

F

Felipe De Sousa E Melo

A

Andrew Mancini

M

Matthew Wongchenko

Y

Yi Shi

School of Materials Science and Engineering, Key Laboratory for Polymeric Composite and Functional Materials of Ministry of Education, Guangdong Functional Biomaterials Engineering Technology Research Center

D

David Shames

Y

Yibing Yan

F

Fortunato Ciardiello

C

Carlos Bais