Late-stage adenine N6-alkylation of nucleos(t)ides and oligonucleotides via photoredox and copper co-catalytic decarboxylative C(sp3)–N coupling
R
Ruoqian Xie
(State Key Laboratory of Synergistic Chem-Bio Synthesis, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, School of Chemistry and Chemical Engineering)
G
Guolan Xiao
W
Wanlu Li
W
Wenhao Luochen
M
Madiha Butt
Y
Yingchuan Que
(State Key Laboratory of Synergistic Chem-Bio Synthesis, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, School of Chemistry and Chemical Engineering)
X
Xiaorong Li
Y
Yangyan Li
(State Key Laboratory of Synergistic Chem-Bio Synthesis, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, School of Chemistry and Chemical Engineering)
L
Litao Sun
(School of Public Health (Shenzhen), Shenzhen Campus of Sun Yat-sen University)
G
Gang Chen
Article Details
Journal
Nature Communications
Volume / Issue
Vol. 17, Issue 1
Published
December 21, 2025
ISSN
2041-1723
Publisher
Nature Portfolio
Authors (10)
R
Ruoqian Xie
State Key Laboratory of Synergistic Chem-Bio Synthesis, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, School of Chemistry and Chemical Engineering
G
Guolan Xiao
W
Wanlu Li
W
Wenhao Luochen
M
Madiha Butt
Y
Yingchuan Que
State Key Laboratory of Synergistic Chem-Bio Synthesis, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, School of Chemistry and Chemical Engineering
X
Xiaorong Li
Y
Yangyan Li
State Key Laboratory of Synergistic Chem-Bio Synthesis, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, School of Chemistry and Chemical Engineering
L
Litao Sun
School of Public Health (Shenzhen), Shenzhen Campus of Sun Yat-sen University
G
Gang Chen
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