Lactylation at lysine 145 fosters KAT8-TIP60 complex formation to promote p53 acetylation at lysine 120 and its pro-apoptotic function
H
Huashan Liu
Z
Ze Li
D
Dongxu Lei
H
Hao Xie
(Beijing National Laboratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences)
X
Xuanhua Yang
C
Chi Zhou
(State Key Laboratory of Elemento-Organic Chemistry, Frontiers Science Center for New Organic Matter, College of Chemistry)
S
Shujuan Li
W
Wenxin Li
(Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism, Key Laboratory for Ultrafine Materials of Ministry of Education, Frontiers Science Center for Materiobiology and Dynamic Chemistry, Engineering Research Center for Biomedical Materials of Ministry of Education, School of Materials Science and Engineering)
Z
Ziwei Zeng
L
Liang Kang
Article Details
Journal
Nature Communications
Volume / Issue
Vol. 17, Issue 1
Published
March 26, 2026
ISSN
2041-1723
Publisher
Nature Portfolio
Authors (10)
H
Huashan Liu
Z
Ze Li
D
Dongxu Lei
H
Hao Xie
Beijing National Laboratory for Condensed Matter Physics, Institute of Physics, Chinese Academy of Sciences
X
Xuanhua Yang
C
Chi Zhou
State Key Laboratory of Elemento-Organic Chemistry, Frontiers Science Center for New Organic Matter, College of Chemistry
S
Shujuan Li
W
Wenxin Li
Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism, Key Laboratory for Ultrafine Materials of Ministry of Education, Frontiers Science Center for Materiobiology and Dynamic Chemistry, Engineering Research Center for Biomedical Materials of Ministry of Education, School of Materials Science and Engineering
Z
Ziwei Zeng
L
Liang Kang
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