Lactate activates trained immunity by fueling the tricarboxylic acid cycle and regulating histone lactylation

H Huanhuan Cai X Xueyuan Chen Y Yan Liu Y Yingbo Chen G Gechang Zhong X Xiaoyu Chen S Shuo Rong H Hao Zeng (Department of Ophthalmology, Shanghai Changhai Hospital, Naval Medical University) L Lin Zhang Z Zelong Li (Key Laboratory of Advanced Catalysis, Gansu Province; State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering) A Aihua Liao X Xiangtai Zeng W Wei Xiong C Cihang Guo Y Yanfang Zhu K Ke-Qiong Deng H Hong Ren H Huan Yan Z Zeng Cai K Ke Xu L Li Zhou Z Zhibing Lu F Fubing Wang S Shi Liu (Department of Chemistry, School of Science and Research Center for Industries of the Future)

Article Details

Volume / Issue Vol. 16, Issue 1
Published April 04, 2025
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (24)

H

Huanhuan Cai

X

Xueyuan Chen

Y

Yan Liu

Y

Yingbo Chen

G

Gechang Zhong

X

Xiaoyu Chen

S

Shuo Rong

H

Hao Zeng

Department of Ophthalmology, Shanghai Changhai Hospital, Naval Medical University

L

Lin Zhang

Z

Zelong Li

Key Laboratory of Advanced Catalysis, Gansu Province; State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering

A

Aihua Liao

X

Xiangtai Zeng

W

Wei Xiong

C

Cihang Guo

Y

Yanfang Zhu

K

Ke-Qiong Deng

H

Hong Ren

H

Huan Yan

Z

Zeng Cai

K

Ke Xu

L

Li Zhou

Z

Zhibing Lu

F

Fubing Wang

S

Shi Liu

Department of Chemistry, School of Science and Research Center for Industries of the Future