Nature Communications

Iterative discovery of potent polymeric antibiotics via multi-stage and multi-task learning against antimicrobial resistance

Y Yuhui Wu C Cong Wang (Key Laboratory of Preclinical Study for New Drugs of Gansu Province, School of Basic Medical Sciences & Research Unit of Peptide Science, Chinese Academy of Medical Sciences, 2019RU066) X Xintian Shen Y Yan Chen H Haiping Wang (State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences) B Bocheng Xu Z Zihao Zhu (MOE Key Laboratory of Macromolecule Synthesis and Functionalization of Ministry of Education, Department of Polymer Science and Engineering) Y Yifeng Chen (Key Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering, Feringa Nobel Prize Scientist Joint Research Center, Frontiers Science Center for Materiobiology and Dynamic Chemistry, School of Chemistry and Molecular Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China) W Wenbin Dai (MOE Key Laboratory of Macromolecule Synthesis and Functionalization of Ministry of Education, Department of Polymer Science and Engineering) Y Yue Huang L Lingyun Zou J Jian Ji (State Key Laboratory of Transvascular Implantation Devices, Department of Cardiology, The Second Affiliated Hospital, School of Medicine) P Peng Zhang
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Article Details

Volume / Issue Vol. 17, Issue 1
Published January 21, 2026
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio
ISSN: 2041-1723 Open Access Life Sciences

Authors (13)

Y

Yuhui Wu

C

Cong Wang

Key Laboratory of Preclinical Study for New Drugs of Gansu Province, School of Basic Medical Sciences & Research Unit of Peptide Science, Chinese Academy of Medical Sciences, 2019RU066

X

Xintian Shen

Y

Yan Chen

H

Haiping Wang

State Key Laboratory of Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences

B

Bocheng Xu

Z

Zihao Zhu

MOE Key Laboratory of Macromolecule Synthesis and Functionalization of Ministry of Education, Department of Polymer Science and Engineering

Y

Yifeng Chen

Key Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering, Feringa Nobel Prize Scientist Joint Research Center, Frontiers Science Center for Materiobiology and Dynamic Chemistry, School of Chemistry and Molecular Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, China

W

Wenbin Dai

MOE Key Laboratory of Macromolecule Synthesis and Functionalization of Ministry of Education, Department of Polymer Science and Engineering

Y

Yue Huang

L

Lingyun Zou

J

Jian Ji

State Key Laboratory of Transvascular Implantation Devices, Department of Cardiology, The Second Affiliated Hospital, School of Medicine

P

Peng Zhang

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