Iterative Bump-and-Hole Engineering Creates a Bioorthogonal Reporter for
                    <i>N</i>
                    -Acetylglucosaminyltransferase I

Yu Liu; Saskia Pieters; Ganka Bineva-Todd; Mert Sagiroglugil; Sean A. Burnap; Freya Hoddle; Anna Cioce; Andre Ohara; Sophie D. Schmidt; Kevin Bruemmer; Carolyn R. Bertozzi; Karen Polizzi; Weston B. Struwe; Carme Rovira; Benjamin Schumann

doi:10.1021/jacs.6c01114

Journal of the American Chemical Society

Iterative Bump-and-Hole Engineering Creates a Bioorthogonal Reporter for <i>N</i> -Acetylglucosaminyltransferase I

Y Yu Liu S Saskia Pieters (Department of Chemistry) G Ganka Bineva-Todd (Chemical Glycobiology Laboratory) M Mert Sagiroglugil (Departament de Química Inorgànica i Orgànica (Secció de Química Orgànica) and Institut de Química Teòrica i Computacional (IQTCUB)) S Sean A. Burnap (Department of Biochemistry, Dorothy Crowfoot Hodgkin Building) F Freya Hoddle (Department of Chemistry) A Anna Cioce (Department of Chemistry) A Andre Ohara (Department of Chemical Engineering) S Sophie D. Schmidt (Department of Chemistry) K Kevin Bruemmer (Stanford Sarafan ChEM-H) C Carolyn R. Bertozzi K Karen Polizzi (Department of Chemical Engineering) W Weston B. Struwe C Carme Rovira (Departament de Química Inorgànica i Orgànica (Secció de Química Orgànica) and Institut de Química Teòrica i Computacional (IQTCUB)) B Benjamin Schumann (Department of Chemistry)

Download PDF View Original

APA MLA Chicago BibTeX RIS

Article Details

Journal Journal of the American Chemical Society

Volume / Issue Vol. 148, Issue 27

Published July 15, 2026

Pages 28190-28201

DOI 10.1021/jacs.6c01114

ISSN 0002-7863

Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (15)

Y

Yu Liu

S

Saskia Pieters

Department of Chemistry

G

Ganka Bineva-Todd

Chemical Glycobiology Laboratory

M

Mert Sagiroglugil

Departament de Química Inorgànica i Orgànica (Secció de Química Orgànica) and Institut de Química Teòrica i Computacional (IQTCUB)

S

Sean A. Burnap

Department of Biochemistry, Dorothy Crowfoot Hodgkin Building

F

Freya Hoddle

Department of Chemistry

A

Anna Cioce

Department of Chemistry

A

Andre Ohara

Department of Chemical Engineering

S

Sophie D. Schmidt

Department of Chemistry

K

Kevin Bruemmer

Stanford Sarafan ChEM-H

C

Carolyn R. Bertozzi

K

Karen Polizzi

Department of Chemical Engineering

W

Weston B. Struwe

C

Carme Rovira

Departament de Química Inorgànica i Orgànica (Secció de Química Orgànica) and Institut de Química Teòrica i Computacional (IQTCUB)

B

Benjamin Schumann

Department of Chemistry

Iterative Bump-and-Hole Engineering Creates a Bioorthogonal Reporter for <i>N</i> -Acetylglucosaminyltransferase I

Article Details

Journal Info

Authors (15)

Related Articles from this Journal

Rational Design of the Composite Perfluoro-Sulfonic Ionomer for High-Performance Proton Exchange Membrane Fuel Cells

Ti3+-O Acid–Base Pairs for Efficient Solar-Driven Photothermal Nonoxidative Ethane Dehydrogenation

Total Synthesis of Benthol A: Evidence for a Structure Revision

Accelerated Self-Photopolymerization of Phenolics in Microdroplets Contributes to the Brown Carbon Formation

Deciphering the Specificity of Reversible DNA-Phosphate ADP-Ribosylation via the Precise Synthesis and Enzymatic Profiling of Nucleotide-Phospho-ADP-Ribosyl Probes