Ion channel inhibition by targeted recruitment of NEDD4-2 with divalent nanobodies
A
Arden Darko-Boateng
E
Emmanuel Afriyie
T
Travis J. Morgenstern
(Department of Antibody Engineering, Genentech Inc.)
S
Sri Karthika Shanmugam
X
Xinle Zou
Y
Yianni D. Laloudakis
P
Papiya Choudhury
M
Meera Desai
R
Robert S. Kass
F
Francesca Vallese
O
Oliver B. Clarke
H
Henry M. Colecraft
Article Details
Journal
Nature Communications
Volume / Issue
Vol. 17, Issue 1
Published
December 06, 2025
ISSN
2041-1723
Publisher
Nature Portfolio
Authors (12)
A
Arden Darko-Boateng
E
Emmanuel Afriyie
T
Travis J. Morgenstern
Department of Antibody Engineering, Genentech Inc.
S
Sri Karthika Shanmugam
X
Xinle Zou
Y
Yianni D. Laloudakis
P
Papiya Choudhury
M
Meera Desai
R
Robert S. Kass
F
Francesca Vallese
O
Oliver B. Clarke
H
Henry M. Colecraft
Related Articles from this Journal
Synthesis of adaptive 15N-nitrosyl-Co7 nanocluster for electrocatalytic C–H functionalization
Chao Wu, Xu Zhang et al.
Aug 2026
10.1038/s41467-026-76516-1
Pan-Ebolavirus nanoparticle vaccine provides protection in rodents from lethal infection by Zaire and Sudan viruses
Connor Weidle, Natalie Brunette et al.
Aug 2026
10.1038/s41467-026-76114-1
Multi-population GWAS meta-analysis identifies bladder cancer susceptibility loci and highlights genetic regulation of smoking-related risk
Ludmila Prokunina-Olsson, Oscar Florez-Vargas et al.
Aug 2026
10.1038/s41467-026-76157-4
Genome-wide annotation of human multi-nucleotide variants reveals widespread functional differences from single nucleotide variants
Weiwei Jin, Wen Cao et al.
Aug 2026
10.1038/s41467-026-76470-y
Allele-specific chromatin architecture shapes imprinted domains and coordinates a distal enhancer and antisense transcription at the mouse Mest-Copg2 domain
Bongmin Bae, Katherine Gu et al.
Aug 2026
10.1038/s41467-026-76506-3